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4F-MPH: Difference between revisions
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'''4F-MPH''' ('''4'-fluoro-methylphenidate''') is an [[entactogenic]] [[stimulant]], [[substituted phenethylamine]], [[piperidine]], and close analog of [[methylphenidate]] (ritalin). The two substances have very similar pharmacological mechanisms but distinctively different subjective effects as ethylphenidate can be considered as significantly more euphoric and recreational in its experience. It also | '''4F-MPH''' ('''4'-fluoro-methylphenidate''') is an [[entactogenic]] [[stimulant]], [[substituted phenethylamine]], [[piperidine]], and close analog of [[methylphenidate]] (ritalin). The two substances have very similar pharmacological mechanisms but distinctively different subjective effects as ethylphenidate can be considered as significantly more euphoric and recreational in its experience. It also acts as a higher efficiency dopamine reuptake inhibitor than the closely related methylphenidate.<ref>Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs | https://www.ncbi.nlm.nih.gov/pubmed/8632426</ref><ref>Biochemical and behavioral characterization of novel methylphenidate analogs | https://www.ncbi.nlm.nih.gov/pubmed/11961053</ref><ref>Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites | https://www.ncbi.nlm.nih.gov/pubmed/15026075</ref><ref>Quantitative structure-activity relationship studies of threo-methylphenidate analogs | https://www.ncbi.nlm.nih.gov/pubmed/20846865</ref>[5]. | ||
4F-MPH has little to no history of human usage prior to its distribution online through research chemical vendors. It was initially developed as replacement for [[ethylphenidate]] which became illegal in the United Kingdom as of Friday 10th April 2015 due to a temporary blanket ban. Annecdotal reports are suggesting that it is considerably more potent with fewer uncomfortable side effects such as [[anxiety]], [[muscle spasms]] and [[compulsive redosing]].<ref>http://www.bluelight.org/vb/threads/770658-4-Fluoromethylphenidate-(4F-MPH)</ref> | 4F-MPH has little to no history of human usage prior to its distribution online through research chemical vendors. It was initially developed as replacement for [[ethylphenidate]] which became illegal in the United Kingdom as of Friday 10th April 2015 due to a temporary blanket ban. Annecdotal reports are suggesting that it is considerably more potent with fewer uncomfortable side effects such as [[anxiety]], [[muscle spasms]] and [[compulsive redosing]].<ref>http://www.bluelight.org/vb/threads/770658-4-Fluoromethylphenidate-(4F-MPH)</ref> | ||
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==Subjective effects== | ==Subjective effects== | ||
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The effects listed below are based upon the [[subjective effects index]] and personal experiences of [[PsychonautWiki]] [[Special:TopUsers|contributors]]. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects. | The effects listed below are based upon the [[subjective effects index]] and personal experiences of [[PsychonautWiki]] [[Special:TopUsers|contributors]]. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects. | ||
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==Legal issues== | ==Legal issues== | ||
4F-MPH is not yet controlled internationally and remains freely available through the use of online research chemical vendors. This means that it is not known to be specifically illegal within any country, but people may still be charged for its possession under certain circumstances such as under analogue laws and with intent to sell or consume. | 4F-MPH is not yet controlled internationally and remains freely available through the use of online research chemical vendors. This means that it is not known to be specifically illegal within any country, but people may still be charged for its possession under certain circumstances such as under analogue laws and with intent to sell or consume. | ||
==See also== | |||
*[[Methylphenidate]] | |||
*[[Ethylphenidate]] | |||
*[[Stimulant]] | |||
==External links== | |||
*[https://en.wikipedia.org/wiki/4-Fluoromethylphenidate 4F-MPH (Wikipedia)] | |||
*[http://www.bluelight.org/vb/threads/770658-4-Fluoromethylphenidate-(4F-MPH) 4F-MPH (Bluelight)] | |||
* | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Psychoactive substances]] | [[Category:Psychoactive substances]] | ||
[[Category:Piperidine]] | [[Category:Piperidine]] | ||
[[Category:Stimulant]] | [[Category:Stimulant]] | ||