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Dihydrocodeine: Difference between revisions
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Dihydrocodeine shares similar chemical structure to codeine, but lacks the double bond. This results in a much more stable chemical structure and also affects its metabolism. Dihydrocodeine can be synthesised from morphine by reduction of the 7,8-double bond. It readily converts to [[dihydromorphine]] with high yields (>95%) which can be methylated to create dihydrocodeine. | Dihydrocodeine shares similar chemical structure to codeine, but lacks the double bond. This results in a much more stable chemical structure and also affects its metabolism. Dihydrocodeine can be synthesised from morphine by reduction of the 7,8-double bond. It readily converts to [[dihydromorphine]] with high yields (>95%) which can be methylated to create dihydrocodeine. | ||
Dihydrocodeine, or 4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-6-ol, is an opioid of the morphinan class. | Dihydrocodeine, or 4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-6-ol, is an opioid of the morphinan class. Dihydrocodeine and other molecules of this class contain a polycyclic core of three benzene rings fused in a zig-zag pattern, called phenanthrene. | ||
==Pharmacology== | ==Pharmacology== | ||