Harmala alkaloid: Difference between revisions

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==Toxicity and harm potential==
==Toxicity and harm potential==
===Drug interactions===
===Drug interactions===
While safer than general [[MAOIs]], RIMAs still have highly dangerous and sometimes fatal interactions with many common drugs. In particular, they can cause [[serotonin syndrome]] or hypertensive crisis when combined with almost any [[antidepressant]], [[stimulant]], common migraine medications, certain herbs, most cold medicines (including decongestants, [[antihistamines]], and cough syrup), nicotine, caffeine, etc. Sedatives are likely easier tolerated, but potentiation should be expected.
While safer than general [[MAOIs]], RIMAs still have highly dangerous and sometimes fatal interactions with many common drugs. In particular, they can cause [[serotonin syndrome]] or hypertensive crisis when combined with almost any [[antidepressant]], [[stimulant]], common migraine medication, certain herbs, most cold medicine (including decongestants, [[antihistamines]], and cough syrup), nicotine, caffeine, etc. Sedatives are likely easier tolerated, but potentiation should be expected.


===Lethal dosage===
===Lethal dosage===