Harmala alkaloid: Difference between revisions

>Oskykins
>Oskykins
No edit summary
Line 13: Line 13:
However, it is important to understand that this does not imply that harmala alkaloids will not cause neurotoxicity. Harmala alkaloids temporarily disable the brain's primary mechanism for breaking down neurotransmitters and drugs which can have negative consequences as material builds up in the synapses, leading to a huge range of downstream central and peripheral effects including [[Sedation|sedation]], [[Stimulation|stimulation]], [[Anxiety|anxiety]], [[cognitive dysphoria]], [[Physical euphoria|euphoria]], [[Headaches|headaches]], [[eye strain]], and [[muscle convulsions]].
However, it is important to understand that this does not imply that harmala alkaloids will not cause neurotoxicity. Harmala alkaloids temporarily disable the brain's primary mechanism for breaking down neurotransmitters and drugs which can have negative consequences as material builds up in the synapses, leading to a huge range of downstream central and peripheral effects including [[Sedation|sedation]], [[Stimulation|stimulation]], [[Anxiety|anxiety]], [[cognitive dysphoria]], [[Physical euphoria|euphoria]], [[Headaches|headaches]], [[eye strain]], and [[muscle convulsions]].


Since [[DMT]] is broken down by monoamine oxidase-A, inhibition of this enzyme allows for the oral activation of DMT and prolongs the experience for the duration of the harmala alkaloid effects. In combination, harmala alkaloids and DMT are known as [[ayahuasca]].
Since [[DMT]] is broken down by monoamine oxidase A, inhibition of this enzyme allows for the oral activation of DMT and prolongs the experience for the duration of the harmala alkaloid effects. In combination, harmala alkaloids and DMT are known as [[ayahuasca]].


==Examples==
==Examples==