Harmala alkaloid: Difference between revisions

>Oskykins
>Oskykins
Line 15: Line 15:


==Examples==
==Examples==
Common Harmala alkaloids include:
Common harmala alkaloids include:


====Harmine====
====Harmine====
[[Image:Harmine2.png|278px]]
[[Image:Harmine2.png|278px]]


'''Harmine''' is a reversible inhibitor of MAO-A (RIMA) at dosages of 200mg.
'''Harmine''' is a reversible inhibitor of MAO-A (RIMA) at doses of 200mg.


====Harmaline====
====Harmaline====
[[Image:Harmaline2.png|278px]]
[[Image:Harmaline2.png|278px]]


'''Harmaline''' is a reversible inhibitor of MAO-A (RIMA) at dosages of 100mg.
'''Harmaline''' is a reversible inhibitor of MAO-A (RIMA) at doses of 100mg.


====Tetrahydroharmine====
====Tetrahydroharmine====
[[Image:Tetrahydroharmine2.png|288px]]
[[Image:Tetrahydroharmine2.png|288px]]


'''Tetrahydroharmine''' does not inhibit monoamine oxidase A. Instead, it weakly inhibits [[serotonin]] [[Reuptake inhibitor|reuptake inhibition]]. At dosages of 200mg, it has been reported to cause dream-like euphoria, pleasurable tingling sensations and a general array of [[psychedelic]] effects.
'''Tetrahydroharmine''' does not inhibit monoamine oxidase A. Instead, it weakly inhibits [[serotonin]] [[Reuptake inhibitor|reuptake inhibition]]. At doses of 200mg, it has been reported to cause dream-like euphoria, pleasurable tingling sensations and a general array of [[psychedelic]] effects.


==Toxicity and harm potential==
==Toxicity and harm potential==