Benzodiazepines: Difference between revisions

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[[File:Benzodiazepine.png|227px|thumb|right|The core structure of benzodiazepines]]

[[File:Benzodiazepine.png|227px|thumb|right|The core structure of benzodiazepines]]{{FUCKBENZOS}}

'''Benzodiazepines''' (also referred to as '''benzos''') are psychoactive drugs that act as central nervous system [[depressants]]. These drugs work by magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid ([[GABA]]) by acting on its receptors.<ref>Benzodiazepine interactions with GABA receptors | http://www.ncbi.nlm.nih.gov/pubmed/6147796</ref> The prominent effects of benzodiazepines include sedation, muscle relaxation, disinhibition, and amnesia. Short-acting benzodiazepines are recommended for treating insomnia while long-acting ones are recommended for the treatment of anxiety disorders.

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Duration and severity of symptoms depends on a number of factors including the half life of the drug used, tolerance and the duration of abuse. Major symptoms will usually start within just a few days after discontinuation and persist for around a week for shorter lasting benzodiazepines. Benzodiazepines with longer half-lives will exhibit discontinuation symptoms with a slow onset and extended duration.

==~~Preparation~~==

==Recipes and preparation methods==

~~{{Main|~~Benzodiazepine solution}}

*'''[[Benzodiazepine solution]]''' - if one's benzos are in powder form they are unlikely to weigh out accurately without the most expensive of scales due to their extreme potency. To avoid this one can dissolve the [[benzodiazepine]] volumetrically into a solution and dose it accurately based upon the methodological instructions linked within this tutorial [[Benzodiazepine solution|here]].

~~Many benzodiazepines~~ are ~~active at 1mg or less~~. In the ~~interest of harm reduction,~~ it ~~is important to prepare~~ [[Benzodiazepine solution|~~solutions~~]] ~~from any pure powder material~~.

==See also==

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-[[File:Benzodiazepine.png|227px|thumb|right|The core structure of benzodiazepines]]
+[[File:Benzodiazepine.png|227px|thumb|right|The core structure of benzodiazepines]]{{FUCKBENZOS}}
 '''Benzodiazepines''' (also referred to as '''benzos''') are psychoactive drugs that act as central nervous system [[depressants]]. These drugs work by magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid ([[GABA]]) by acting on its receptors.<ref>Benzodiazepine interactions with GABA receptors | http://www.ncbi.nlm.nih.gov/pubmed/6147796</ref> The prominent effects of benzodiazepines include sedation, muscle relaxation, disinhibition, and amnesia. Short-acting benzodiazepines are recommended for treating insomnia while long-acting ones are recommended for the treatment of anxiety disorders.
@@ Line 53: / Line 53: @@
 Duration and severity of symptoms depends on a number of factors including the half life of the drug used, tolerance and the duration of abuse. Major symptoms will usually start within just a few days after discontinuation and persist for around a week for shorter lasting benzodiazepines. Benzodiazepines with longer half-lives will exhibit discontinuation symptoms with a slow onset and extended duration.
-==Preparation==
+==Recipes and preparation methods==
-{{Main|Benzodiazepine solution}}
+*'''[[Benzodiazepine solution]]''' - if one's benzos are in powder form they are unlikely to weigh out accurately without the most expensive of scales due to their extreme potency. To avoid this one can dissolve the [[benzodiazepine]] volumetrically into a solution and dose it accurately based upon the methodological instructions linked within this tutorial [[Benzodiazepine solution|here]].
-Many benzodiazepines are active at 1mg or less. In the interest of harm reduction, it is important to prepare [[Benzodiazepine solution|solutions]] from any pure powder material.
 ==See also==