Dihydrocodeine: Difference between revisions
>Kaylee |
>Oskykins |
||
Line 11: | Line 11: | ||
Dihydrocodeine is also the original member and chemical base of a number of similar semi-synthetic opiates such as [[acetyldihydrocodeine]], [[dihydrocodeine enol acetate]], [[dihydroisocodeine]], [[nicocodeine]], and [[nicodicodeine]]. | Dihydrocodeine is also the original member and chemical base of a number of similar semi-synthetic opiates such as [[acetyldihydrocodeine]], [[dihydrocodeine enol acetate]], [[dihydroisocodeine]], [[nicocodeine]], and [[nicodicodeine]]. | ||
==Chemistry== | ==Chemistry== | ||
Dihydrocodeine shares similar chemical structure to codeine but lacks the double bond. This results in a much more stable chemical structure | Dihydrocodeine shares similar chemical structure to codeine, but lacks the double bond. This results in a much more stable chemical structure and also affects its metabolism. Dihydrocodeine can be synthesised from morphine by reduction of the 7,8-double bond. It readily converts to dihydromorphine with high yields (>95%). | ||
==Pharmacology== | ==Pharmacology== |