Antipsychotic: Difference between revisions
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'''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>http://books.google.ca/books?id=Q4hG2gRhy7oC&pg=PA151</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[ | '''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>http://books.google.ca/books?id=Q4hG2gRhy7oC&pg=PA151</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[Delusion|delusions]], hallucinations, or disordered thought), in particular in [[schizophrenia]] and bipolar disorder]]. The word '''neuroleptic''' originates from the Greek word "''νεῦρον''", ''neuron'' ("nerve") and ''lepsis'' ("seizure" or "fit"). | ||
First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, [[clozapine]], was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's [[dopamine]] pathways, but atypicals tend to act on [[serotonin]] receptors as well. | First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, [[clozapine]], was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's [[dopamine]] pathways, but atypicals tend to act on [[serotonin]] receptors as well. |