Routes of administration: Difference between revisions

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Sublingual administration refers to absorption under the tounge. It is a common route of administration for drugs such as [[LSD]]. Sublingual administration can result in a fast absorption bypassing the GI tracts tendency to break down certain drugs, such as [[25I-NBOMe]], which absorbs sublingual and buccal but not orally. Sublingual administration results in the substance being absorbed through the large Lingual artery present underneath the tounge.

===Buccal===

Buccal administration refers to absorption in the cheek and gum. This is commonly employed when ingesting drugs such as [[25I-NBOMe|25I-NBOMe]], [[LSD]], and other substances impregnated on blotter paper. Like sublingual, the substance is largely absorbed through the lingual artery but is also absorbed through gum lining. This method is also ~~employed~~ when chewing plant leaves such as [[Khat]], [[Salvia Divinorum]], and commonly [[Tobacco]].

Buccal administration refers to absorption in the cheek and gum. This is commonly employed when ingesting drugs such as [[25I-NBOMe|25I-NBOMe]], [[LSD]], and other substances impregnated on blotter paper. Like sublingual, the substance is largely absorbed through the lingual artery but is also absorbed through gum lining. This method is also used when chewing plant leaves such as [[Khat]], [[Salvia Divinorum]], and commonly [[Tobacco]].

===Insufflation===

Insufflation is a very common method for substances in powder form. Insufflation is capable of rapid absorption through mucous membranes and blood vessels in the sinus. Absorption is generally much more rapid and subsequently a substance feels much more intense and often shorter acting than if taken orally. Insufflation is common among drugs such as cocaine, but is also known amongnst yopo rituals, and insufflating tobacco in snuff form was common practice in the 20th century.

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 Sublingual administration refers to absorption under the tounge. It is a common route of administration for drugs such as [[LSD]]. Sublingual administration can result in a fast absorption bypassing the GI tracts tendency to break down certain drugs, such as [[25I-NBOMe]], which absorbs sublingual and buccal but not orally. Sublingual administration results in the substance being absorbed through the large Lingual artery present underneath the tounge.
 ===Buccal===
-Buccal administration refers to absorption in the cheek and gum. This is commonly employed when ingesting drugs such as [[25I-NBOMe|25I-NBOMe]], [[LSD]], and other substances impregnated on blotter paper. Like sublingual, the substance is largely absorbed through the lingual artery but is also absorbed through gum lining. This method is also employed when chewing plant leaves such as [[Khat]], [[Salvia Divinorum]], and commonly [[Tobacco]].
+Buccal administration refers to absorption in the cheek and gum. This is commonly employed when ingesting drugs such as [[25I-NBOMe|25I-NBOMe]], [[LSD]], and other substances impregnated on blotter paper. Like sublingual, the substance is largely absorbed through the lingual artery but is also absorbed through gum lining. This method is also used when chewing plant leaves such as [[Khat]], [[Salvia Divinorum]], and commonly [[Tobacco]].
 ===Insufflation===
 Insufflation is a very common method for substances in powder form. Insufflation is capable of rapid absorption through mucous membranes and blood vessels in the sinus. Absorption is generally much more rapid and subsequently a substance feels much more intense and often shorter acting than if taken orally. Insufflation is common among drugs such as cocaine, but is also known amongnst yopo rituals, and insufflating tobacco in snuff form was common practice in the 20th century.