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25I-NBOMe: Difference between revisions
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==Pharmacology== | ==Pharmacology== | ||
{{Main|Serotonergic psychedelic}} | |||
25I-NBOMe is pharmacologically unique when compared to other psychedelics through its action on [[serotonin]] receptors. It is one of the only [[Agonist#Agonists|full agonists]] for the human [[Serotonin#The 5-HT System|5-HT<sub>2A</sub> receptor]] receptor in existence.<ref name="pmid21174090">Ettrup, A. E. A. ; Hansen, M.; Santini, M. A.; Paine, J.; Gillings, N.; Palner, M.; Lehel, S.; Herth, M. M.; Madsen, J. (2010). "Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers". European Journal of Nuclear Medicine and Molecular Imaging 38 (4): 681–693. | http://www.ncbi.nlm.nih.gov/pubmed/21174090</ref> In comparison, classical psychedelics such as [[LSD]], [[DMT]] and [[psilocin]] can only be considered [[Agonist#Agonists|partial agonists]]. However, the role of these interactions and how they result in the [[psychedelic]] experience continues to remain elusive. | 25I-NBOMe is pharmacologically unique when compared to other psychedelics through its action on [[serotonin]] receptors. It is one of the only [[Agonist#Agonists|full agonists]] for the human [[Serotonin#The 5-HT System|5-HT<sub>2A</sub> receptor]] receptor in existence.<ref name="pmid21174090">Ettrup, A. E. A. ; Hansen, M.; Santini, M. A.; Paine, J.; Gillings, N.; Palner, M.; Lehel, S.; Herth, M. M.; Madsen, J. (2010). "Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers". European Journal of Nuclear Medicine and Molecular Imaging 38 (4): 681–693. | http://www.ncbi.nlm.nih.gov/pubmed/21174090</ref> In comparison, classical psychedelics such as [[LSD]], [[DMT]] and [[psilocin]] can only be considered [[Agonist#Agonists|partial agonists]]. However, the role of these interactions and how they result in the [[psychedelic]] experience continues to remain elusive. | ||