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DOx: Difference between revisions
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[[File:DOx.svg|250px|thumbnail|The generic structure for a DOx compound]] | [[File:DOx.svg|250px|thumbnail|The generic structure for a DOx compound]] | ||
'''Substituted | '''Substituted dimethoxyamphetamines''' (also known as '''DOx''') refers to a class of psychedelic [[amphetamine]]s originally synthesized and documented by [[Alexander Shulgin]] in his investigation of psychoactive [[phenethylamine]]s in the 1970s. Shulgin later published his findings along with other mescaline-derived compounds in his semi-autobiographical book/organic synthesis reference [[PiHKAL]] ("Phenethylamines I Have Known and Loved")<ref>{{Citation | title=Erowid Online Books : “PIHKAL” - The Chemical Story | url=https://erowid.org/library/books_online/pihkal/pihkal.shtml}}</ref>. | ||
The DOx compounds are highly potent, dose-sensitive, and long-lasting substances which are considered considerably more intense and challenging to use than their counterpart [[2C-x]] analogs as well as the [[serotonin|serotonergic]] [[lysergamides]]. The effects of DOx are comprised of strong visuals and an intense body load that is typically accompanied by marked physical and mental stimulation that can persist well past the main duration of its effects (prolonged [[stimulation|residual stimulation]]) | The DOx compounds are highly potent, dose-sensitive, and long-lasting substances which are considered considerably more intense and challenging to use than their counterpart [[2C-x]] analogs as well as the [[serotonin|serotonergic]] [[lysergamides]]. The effects of DOx are comprised of strong visuals and an intense body load that is typically accompanied by marked physical and mental stimulation that can persist well past the main duration of its effects (prolonged [[stimulation|residual stimulation]]). | ||
Notably, they are one of the few classes of psychedelic chemicals (the other being the [[25x-NBOMe]] series and the serotonergic [[lysergamides]]) potent enough by weight to be laid onto and distributed on blotter paper, where it is has a history of being sold as a substitute for genuine [[LSD]], being significantly easier to produce. On the street, they are notorious for their distinctly bitter taste as well as their unusually long come-up period (which can take up to 3-4 hours before its main effects even begin to present themselves), which has sometimes led inexperienced LSD users to prematurely conclude that their tabs must be weak or from a "bunk batch" and then take more to try to compensate; this has led to a number of accidental overdoses and unpleasant and overwhelming experiences when the substance's effects finally do take hold.<ref name="PIHKALDOM">{{Citation | title=Erowid Online Books : “PIHKAL” - #68 DOM | url=https://www.erowid.org/library/books_online/pihkal/pihkal068.shtml}}</ref> | Notably, they are one of the few classes of psychedelic chemicals (the other being the [[25x-NBOMe]] series and the serotonergic [[lysergamides]]) potent enough by weight to be laid onto and distributed on blotter paper, where it is has a history of being sold as a substitute for genuine [[LSD]], being significantly easier to produce. On the street, they are notorious for their distinctly bitter taste as well as their unusually long come-up period (which can take up to 3-4 hours before its main effects even begin to present themselves), which has sometimes led inexperienced LSD users to prematurely conclude that their tabs must be weak or from a "bunk batch" and then take more to try to compensate; this has led to a number of accidental overdoses and unpleasant and overwhelming experiences when the substance's effects finally do take hold.<ref name="PIHKALDOM">{{Citation | title=Erowid Online Books : “PIHKAL” - #68 DOM | url=https://www.erowid.org/library/books_online/pihkal/pihkal068.shtml}}</ref> | ||