Talk:Zaleplon: Difference between revisions

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Zaleplon has a pharmacological profile similar to [[benzodiazepines]]. Zaleplon is a full [[agonist]] for the benzodiazepine a1 [[receptor]] located on the [[GABA]]<sub>A</sub> receptor ionophore complex in the brain, with lower affinity for the a2 and a3 subtypes. It selectively enhances the action of GABA similar to but more selectively than benzodiazepines.<ref name="Zaleplon Pharmacology">Profiles of Drug Substances, Excipients and Related Methodology | https://www.sciencedirect.com/science/article/pii/S1871512510350084</ref>

In regards to how the consumption of this compound results in its bizarre [[hallucinations]], the pharmacological mechanics behind this are not understood and do not seem to have been directly studied. It is worth noting, however, that zaleplon may share similar mechanisms as a [[GABA]]<sub>A</sub> receptor [[agonist]] to that of [[muscimol]], which is the active compound within the hallucinogenic [[amanita muscaria]] mushroom.

In regards to how the consumption of this compound results in its bizarre [[hallucinations]], the pharmacological mechanics behind this are not understood and do not seem to have been directly studied.

==Subjective effects==

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 Zaleplon has a pharmacological profile similar to [[benzodiazepines]]. Zaleplon is a full [[agonist]] for the benzodiazepine a1 [[receptor]] located on the [[GABA]]<sub>A</sub> receptor ionophore complex in the brain, with lower affinity for the a2 and a3 subtypes. It selectively enhances the action of GABA similar to but more selectively than benzodiazepines.<ref name="Zaleplon Pharmacology">Profiles of Drug Substances, Excipients and Related Methodology | https://www.sciencedirect.com/science/article/pii/S1871512510350084</ref>
-In regards to how the consumption of this compound results in its bizarre [[hallucinations]], the pharmacological mechanics behind this are not understood and do not seem to have been directly studied. It is worth noting, however, that zaleplon may share similar mechanisms as a [[GABA]]<sub>A</sub> receptor [[agonist]] to that of [[muscimol]], which is the active compound within the hallucinogenic [[amanita muscaria]] mushroom.
+In regards to how the consumption of this compound results in its bizarre [[hallucinations]], the pharmacological mechanics behind this are not understood and do not seem to have been directly studied.
 ==Subjective effects==