Talk:Dextromethorphan: Difference between revisions

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==Plateau Sigma==

I feel like Plateau Sigma shouldn't be called "Fifth Plateau" and should instead be called as its own distinct plateau. By this distinction I think it'll help drive the point that it does not match with the linear dose-effect relationship of the first to fourth plateaus because it involves a certain hepatic phenomenon from redosing that can create a different subjective effect (by dosage tolerability and ↑DXM:↓DXO blood concentration). On a more off-topic note, I think we should talk about warning against redosing DXM too much throughout the day because of this certain effect (e.g. Redosing after CYP2D6 is being pre-occupied by initial dosages). What do you guys think of this? [[User:Uzi|Uzi]] ([[User talk:Uzi|talk]]) 04:07, 8 June 2024 (UTC)

== Legality ==

In reference to "''United States: Dextromethorphan is available over the counter and can be found in grocery stores, convenience stores, and online. Many physical locations requires the purchaser to be over the age of 18, however this is not the law.''"

This should be elaborated on to include the states where the selling of DXM-containing products is restricted to those 18+ in some states such as New York and New Jersey

Refs: New York State: https://www.nysenate.gov/legislation/bills/2013/s696/amendment/b, New Jersey: https://legiscan.com/NJ/text/A622/id/926720

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 ==Plateau Sigma==
 I feel like Plateau Sigma shouldn't be called "Fifth Plateau" and should instead be called as its own distinct plateau. By this distinction I think it'll help drive the point that it does not match with the linear dose-effect relationship of the first to fourth plateaus because it involves a certain hepatic phenomenon from redosing that can create a different subjective effect (by dosage tolerability and ↑DXM:↓DXO blood concentration). On a more off-topic note, I think we should talk about warning against redosing DXM too much throughout the day because of this certain effect (e.g. Redosing after CYP2D6 is being pre-occupied by initial dosages). What do you guys think of this? [[User:Uzi|Uzi]] ([[User talk:Uzi|talk]]) 04:07, 8 June 2024 (UTC)
+== Legality ==
+In reference to "''United States: Dextromethorphan is available over the counter and can be found in grocery stores, convenience stores, and online. Many physical locations requires the purchaser to be over the age of 18, however this is not the law.''"
+This should be elaborated on to include the states where the selling of DXM-containing products is restricted to those 18+ in some states such as New York and New Jersey
+Refs: New York State: https://www.nysenate.gov/legislation/bills/2013/s696/amendment/b, New Jersey: https://legiscan.com/NJ/text/A622/id/926720