Cocaine/Synthesis: Difference between revisions

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'''Overview'''

Here we are obtaining tropine to create tropinone from a natural source; the anticholinergic tropane alkaloids such as [[atropine]], [[scopolamine]], [[hyocyamine]], mandragovine, and other similar [[Tropane Alkaloids|tropane alkaloids]] obtained from the plants in the [https://en.wikipedia.org/wiki/Solanaceae Solanaceae family], such Belladonna, Datura, Henbane, Brugmansia, and Mandrake. Tropane alkaloids all contain the tropane ring which, when separated from the tropic, scopic, and hyoscopic, and similar acids becomes tropine, which we can use as a source chemical to produce tropinone, which is necessary for creation of synthetic cocaine. These plants grow in most of the parts of the world~~. By using this route to produce cocaine the plants can be grown in country, so the cocaine does not need to be transported very far, making it extremely cheap~~. With this semi-synthetic synthesis we can grow these plants nearly anywhere in the world, make cocaine cheaply within the country without having to transport it or cut it, to ensure harm reduction and that the cartels, traffickers, and other such dangerous criminals are out of a ~~f*cking~~ job.

Here we are obtaining tropine to create tropinone from a natural source; the anticholinergic tropane alkaloids such as [[atropine]], [[scopolamine]], [[hyocyamine]], mandragovine, and other similar [[Tropane Alkaloids|tropane alkaloids]] obtained from the plants in the [https://en.wikipedia.org/wiki/Solanaceae Solanaceae family], such Belladonna, Datura, Henbane, Brugmansia, and Mandrake. Tropane alkaloids all contain the tropane ring which, when separated from the tropic, scopic, and hyoscopic, and similar acids becomes tropine, which we can use as a source chemical to produce tropinone, which is necessary for creation of synthetic cocaine. These plants grow in most of the parts of the world. With this semi-synthetic synthesis we can grow these plants nearly anywhere in the world, make cocaine cheaply within the country without having to transport it or cut it, to ensure harm reduction and that the cartels, traffickers, and other such dangerous criminals are out of a job.

'''Extraction'''

A boiling water extraction is used to extract the [[Tropane Alkaloids|tropane alkaloids]] from the plant material. A sheet of cloth as a filter is put down in a container and water is boiled in said container. The plants are then pulled up by the roots, washed with water, and then placed in the container and pulverized and macerated while under the water with an appropriate utensil such as a piece of wood or a pipe, which is also used to stir the brew. Keeping a lid on the container at all times will preclude spattering, the liquid possibly ~~absorbing~~ through your skin giving you anticholinergic poisoning. After the brew has boiled for some time pull up the cloth as a filter, leaving the extracted alkaloids in the water. Boil down the water for a concentrated solution of [[Tropane Alkaloids|tropane alkaloids]]. Multiple extractions of the same plant matter, and multiple extractions of different plant matter from another vessel(s) and transferred and boiled down in the main vessel will result in a concentrated aqueous solution of [[Tropane Alkaloids|tropane alkaloids]].

A boiling water extraction is used to extract the [[Tropane Alkaloids|tropane alkaloids]] from the plant material. A sheet of cloth as a filter is put down in a container and water is boiled in said container. The plants are then pulled up by the roots, washed with water, and then placed in the container and pulverized and macerated while under the water with an appropriate utensil such as a piece of wood or a pipe, which is also used to stir the brew. Keeping a lid on the container at all times will preclude spattering, as the liquid could possibly absorb through your skin giving you anticholinergic poisoning. After the brew has boiled for some time pull up the cloth as a filter, leaving the extracted alkaloids in the water. Boil down the water for a concentrated solution of [[Tropane Alkaloids|tropane alkaloids]]. Multiple extractions of the same plant matter, and multiple extractions of different plant matter from another vessel(s) and transferred and boiled down in the main vessel will result in a concentrated aqueous solution of [[Tropane Alkaloids|tropane alkaloids]].

'''Hydrolysis'''

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'''Hydrogenation'''

For the hydrogenation reaction above we can use a (sealable) conductive metal container or two conductive metal objects in the ethanoic solution containing the NaOH acting as an electrolyte. We can set up an electrolysis reaction for a sort of sparging situation where hydrogen bubbles up through the (sealable) metal container acting like a hydrogenator. We can use any electricity source we choose, sealing the metal container and allowing the hydrogen gas to bubble up through the ethanoic solution, hydrogenating the 2-Carbomethoxytropinone into methylecgonine. This setup may be much easier and less suspicious than a conventional hydrogenator and can be done in-situ.

For the hydrogenation reaction above we can use a (sealable) conductive metal container or two conductive metal objects in the ethanoic solution containing the NaOH acting as an electrolyte. We can set up an electrolysis reaction for a sort of sparging situation where hydrogen bubbles up through the (sealable) metal container acting like a hydrogenator. We can use any electricity source we choose, sealing the metal container and allowing the hydrogen gas to bubble up through the ethanoic solution, hydrogenating the 2-Carbomethoxytropinone into methylecgonine. This setup may be much easier and less suspicious than a conventional hydrogenator, and can be done in-situ.

'''Fractional Crystallization'''

Cocaine has 16 sterioisomers, different configurations of the cocaine molecule. One of these is the cocaine we are looking for, the other sterioisomers are either inactive, or may be toxic. Since the sterioisomers have the same molecular mass we cannot use chromatography or distillation to separate them. Instead we dissolve the hydrochloride sterioisomers in a heated, aqueous supersaturated solution and then use a seed crystal of the cocaine hydrochloride isomer we are looking for and then lower the temperature of the supersaturated solution. This causes the correct cocaine hydrochloride sterioisomer to crystallize on the seed crystal. This is fractional crystallization and separates the correct sterioisomer from the rest of the other sterioisomers. A cocaine seed crystal can be obtained from an anhydrous acetone wash of street cocaine. Cocaine hydrochloride is completely insoluble in pure, anhydrous acetone, but all cutting agents are, dissolving them away leaving pure cocaine hydrochloride crystals, which can then be used for our fractional crystallization process.

@@ Line 64: / Line 64: @@
 '''Overview'''
-Here we are obtaining tropine to create tropinone from a natural source; the anticholinergic tropane alkaloids such as [[atropine]], [[scopolamine]], [[hyocyamine]], mandragovine, and other similar [[Tropane Alkaloids|tropane alkaloids]] obtained from the plants in the [https://en.wikipedia.org/wiki/Solanaceae Solanaceae family], such Belladonna, Datura, Henbane, Brugmansia, and Mandrake. Tropane alkaloids all contain the tropane ring which, when separated from the tropic, scopic, and hyoscopic, and similar acids becomes tropine, which we can use as a source chemical to produce tropinone, which is necessary for creation of synthetic cocaine. These plants grow in most of the parts of the world. By using this route to produce cocaine the plants can be grown in country, so the cocaine does not need to be transported very far, making it extremely cheap. With this semi-synthetic synthesis we can grow these plants nearly anywhere in the world, make cocaine cheaply within the country without having to transport it or cut it, to ensure harm reduction and that the cartels, traffickers, and other such dangerous criminals are out of a f*cking job.
+Here we are obtaining tropine to create tropinone from a natural source; the anticholinergic tropane alkaloids such as [[atropine]], [[scopolamine]], [[hyocyamine]], mandragovine, and other similar [[Tropane Alkaloids|tropane alkaloids]] obtained from the plants in the [https://en.wikipedia.org/wiki/Solanaceae Solanaceae family], such Belladonna, Datura, Henbane, Brugmansia, and Mandrake. Tropane alkaloids all contain the tropane ring which, when separated from the tropic, scopic, and hyoscopic, and similar acids becomes tropine, which we can use as a source chemical to produce tropinone, which is necessary for creation of synthetic cocaine. These plants grow in most of the parts of the world. With this semi-synthetic synthesis we can grow these plants nearly anywhere in the world, make cocaine cheaply within the country without having to transport it or cut it, to ensure harm reduction and that the cartels, traffickers, and other such dangerous criminals are out of a job.
 '''Extraction'''
-A boiling water extraction is used to extract the [[Tropane Alkaloids|tropane alkaloids]] from the plant material. A sheet of cloth as a filter is put down in a container and water is boiled in said container. The plants are then pulled up by the roots, washed with water, and then placed in the container and pulverized and macerated while under the water with an appropriate utensil such as a piece of wood or a pipe, which is also used to stir the brew. Keeping a lid on the container at all times will preclude spattering, the liquid possibly absorbing through your skin giving you anticholinergic poisoning. After the brew has boiled for some time pull up the cloth as a filter, leaving the extracted alkaloids in the water. Boil down the water for a concentrated solution of [[Tropane Alkaloids|tropane alkaloids]]. Multiple extractions of the same plant matter, and multiple extractions of different plant matter from another vessel(s) and transferred and boiled down in the main vessel will result in a concentrated aqueous solution of [[Tropane Alkaloids|tropane alkaloids]].
+A boiling water extraction is used to extract the [[Tropane Alkaloids|tropane alkaloids]] from the plant material. A sheet of cloth as a filter is put down in a container and water is boiled in said container. The plants are then pulled up by the roots, washed with water, and then placed in the container and pulverized and macerated while under the water with an appropriate utensil such as a piece of wood or a pipe, which is also used to stir the brew. Keeping a lid on the container at all times will preclude spattering, as the liquid could possibly absorb through your skin giving you anticholinergic poisoning. After the brew has boiled for some time pull up the cloth as a filter, leaving the extracted alkaloids in the water. Boil down the water for a concentrated solution of [[Tropane Alkaloids|tropane alkaloids]]. Multiple extractions of the same plant matter, and multiple extractions of different plant matter from another vessel(s) and transferred and boiled down in the main vessel will result in a concentrated aqueous solution of [[Tropane Alkaloids|tropane alkaloids]].
 '''Hydrolysis'''
@@ Line 76: / Line 76: @@
 '''Hydrogenation'''
-For the hydrogenation reaction above we can use a (sealable) conductive metal container or two conductive metal objects in the ethanoic solution containing the NaOH acting as an electrolyte. We can set up an electrolysis reaction for a sort of sparging situation where hydrogen bubbles up through the (sealable) metal container acting like a hydrogenator. We can use any electricity source we choose, sealing the metal container and allowing the hydrogen gas to bubble up through the ethanoic solution, hydrogenating the 2-Carbomethoxytropinone into methylecgonine. This setup may be much easier and less suspicious than a conventional hydrogenator and can be done in-situ.
+For the hydrogenation reaction above we can use a (sealable) conductive metal container or two conductive metal objects in the ethanoic solution containing the NaOH acting as an electrolyte. We can set up an electrolysis reaction for a sort of sparging situation where hydrogen bubbles up through the (sealable) metal container acting like a hydrogenator. We can use any electricity source we choose, sealing the metal container and allowing the hydrogen gas to bubble up through the ethanoic solution, hydrogenating the 2-Carbomethoxytropinone into methylecgonine. This setup may be much easier and less suspicious than a conventional hydrogenator, and can be done in-situ.
 '''Fractional Crystallization'''
 Cocaine has 16 sterioisomers, different configurations of the cocaine molecule. One of these is the cocaine we are looking for, the other sterioisomers are either inactive, or may be toxic. Since the sterioisomers have the same molecular mass we cannot use chromatography or distillation to separate them. Instead we dissolve the hydrochloride sterioisomers in a heated, aqueous supersaturated solution and then use a seed crystal of the cocaine hydrochloride isomer we are looking for and then lower the temperature of the supersaturated solution. This causes the correct cocaine hydrochloride sterioisomer to crystallize on the seed crystal. This is fractional crystallization and separates the correct sterioisomer from the rest of the other sterioisomers. A cocaine seed crystal can be obtained from an anhydrous acetone wash of street cocaine. Cocaine hydrochloride is completely insoluble in pure, anhydrous acetone, but all cutting agents are, dissolving them away leaving pure cocaine hydrochloride crystals, which can then be used for our fractional crystallization process.