NEP: Difference between revisions

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==Subjective effects==

~~===Notice on Crystals vs Powder===~~

Anecdotal evidence shows most recent bathes have drastic difference in potency, especially the NEP Powder, which seems to have 50% potency over the crystals (''very batch dependent''). Keep in mind, that 10mg insufflated when using Crystals could've a drastic different effect from 10mg insufflated NEP Powder. It's recommended to limit yourself to 10mg insufflated per dose, when using the Crystal form<ref name=":1">[https://www.reddit.com/r/researchchemicals/comments/1alawbu/how_to_enjoy_your_shitty_nep_a_quick_guide/ Reddit - Explanation to use the noradrenergic NEP batch]</ref>. The powder form is generally considered the "mild" NEP. Some people prefer the "mild" version of the NEP crystals, since it will cause less heart strain and other negative physical side effects. It looks like the crystals don't seem to be simply crushed to powder. Either an inactive or less active substance seems to added, or another [[Enantiomers|enantiomer]] is found is this batch, which changes the [[Stimulation|stimulating]] effect by a lot{{citation needed}}. Even if

ou have a high tolerance, you will notice the difference between the Crystals and Powder when insufflated (also ''very batch dependent''). The smell of the crystals is also way more prominent and becomes an unpleasant odor. While the powder barely changes in smell, even after a year.

~~Additionally, it seems there're various batches of NEP Crystals, in different forms, even from the same seller/vendor, with different effects from each other.~~

One batch seems to have more noradrenergic effects, and fewer dopaminergic effects, which results in more physical side effects, and fewer cognitive effects.<ref name=":1" /> This batch contains "compressed" white crystals, while better batches, with more subjectively positive dopaminergic effects, seems to look like "uncompressed", transparent crystals, which can also be found in newer batches.{{citation needed}}

{{effects/base

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*'''[[Effect::Tactile enhancement]]'''

*'''[[Effect::Dehydration]]''' - Dry mouth and increased sweating can occur after consuming NEP. Low doses of the substance in question cause minimal dehydration.

*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting~~. although some reports mention moderate to extreme vasoconstriction~~.

*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting.

*'''[[Effect::Abnormal heartbeat]]'''

*'''[[Effect::Increased blood pressure]]'''

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*'''[[Effect::Motivation enhancement]]'''

*'''[[Effect::Compulsive redosing]]'''

*'''[[Effect::Increased libido]]'''

}}

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*'''Sweden''': NEP is a controlled substance as of November 12, 2019.<ref>{{cite web|url=https://svenskforfattningssamling.se/sites/default/files/sfs/2019-10/SFS2019-612.pdf|title=Svensk författningssamling: Förordningom ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor|language=sv|access-date=December 27, 2019|publisher=Thomson Förlag}}</ref>

*'''Switzerland''': NEP can be considered a controlled substance as a defined derivative of Cathinone under Verzeichnis E point 1. It is legal when used for scientific or industrial use.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>

*'''The Netherlands:''' NEP is currently legal, but it is part of a substance group that may be banned soon as part of a recently passed law on New Psychoactive Substances (NPS). <ref>{{Citation|title= Wijziging van de Opiumwet in verband met het toevoegen van een derde lijst met als doel het tegengaan van de productie van en de handel in nieuwe psychoactieve stoffen en enkele andere wijzigingen (Dutch) | year=2024|url=https://www.tweedekamer.nl/kamerstukken/wetsvoorstellen/detail?id=2022Z14042&dossier=36159}}</ref>

*'''United Kingdom''': NEP is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2010 | url=https://www.legislation.gov.uk/uksi/2010/1207/made}}</ref>

*'''United States''': NEP is not a controlled substance in the United States but possession or distribution for human use could potentially be prosecuted under the Federal Analogue Act due to its structural and pharmacological similarities to [[pentedrone]].<ref>{{Citation | title=21 U.S. Code § 813 - Treatment of controlled substance analogues | url=https://www.law.cornell.edu/uscode/text/21/813}}</ref>

@@ Line 19: / Line 19: @@
 ==Subjective effects==
-===Notice on Crystals vs Powder===
-Anecdotal evidence shows most recent bathes have drastic difference in potency, especially the NEP Powder, which seems to have 50% potency over the crystals (''very batch dependent''). Keep in mind, that 10mg insufflated when using Crystals could've a drastic different effect from 10mg insufflated NEP Powder. It's recommended to limit yourself to 10mg insufflated per dose, when using the Crystal form<ref name=":1">[https://www.reddit.com/r/researchchemicals/comments/1alawbu/how_to_enjoy_your_shitty_nep_a_quick_guide/ Reddit - Explanation to use the noradrenergic NEP batch]</ref>. The powder form is generally considered the "mild" NEP. Some people prefer the "mild" version of the NEP crystals, since it will cause less heart strain and other negative physical side effects. It looks like the crystals don't seem to be simply crushed to powder. Either an inactive or less active substance seems to added, or another [[Enantiomers|enantiomer]] is found is this batch, which changes the [[Stimulation|stimulating]] effect by a lot{{citation needed}}. Even if
-ou have a high tolerance, you will notice the difference between the Crystals and Powder when insufflated (also ''very batch dependent''). The smell of the crystals is also way more prominent and becomes an unpleasant odor. While the powder barely changes in smell, even after a year.
-Additionally, it seems there're various batches of NEP Crystals, in different forms, even from the same seller/vendor, with different effects from each other.
-One batch seems to have more noradrenergic effects, and fewer dopaminergic effects, which results in more physical side effects, and fewer cognitive effects.<ref name=":1" /> This batch contains "compressed" white crystals, while better batches, with more subjectively positive dopaminergic effects, seems to look like "uncompressed", transparent crystals, which can also be found in newer batches.{{citation needed}}
 {{Preamble/SubjectiveEffects}}
 {{effects/base
@@ Line 37: / Line 28: @@
 *'''[[Effect::Tactile enhancement]]'''
 *'''[[Effect::Dehydration]]''' - Dry mouth and increased sweating can occur after consuming NEP. Low doses of the substance in question cause minimal dehydration.
-*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting. although some reports mention moderate to extreme vasoconstriction.
+*'''[[Effect::Vasoconstriction]]''' - NEP has been reported as being slightly vasoconstricting.
 *'''[[Effect::Abnormal heartbeat]]'''
 *'''[[Effect::Increased blood pressure]]'''
@@ Line 63: / Line 54: @@
 *'''[[Effect::Motivation enhancement]]'''
 *'''[[Effect::Compulsive redosing]]'''
-*'''[[Effect::Increased libido]]'''
 }}
@@ Line 124: / Line 114: @@
 *'''Sweden''': NEP is a controlled substance as of November 12, 2019.<ref>{{cite web|url=https://svenskforfattningssamling.se/sites/default/files/sfs/2019-10/SFS2019-612.pdf|title=Svensk författningssamling: Förordningom ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor|language=sv|access-date=December 27, 2019|publisher=Thomson Förlag}}</ref>
 *'''Switzerland''': NEP can be considered a controlled substance as a defined derivative of Cathinone under Verzeichnis E point 1. It is legal when used for scientific or industrial use.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>
 *'''The Netherlands:''' NEP is currently legal, but it is part of a substance group that may be banned soon as part of a recently passed law on New Psychoactive Substances (NPS). <ref>{{Citation|title= Wijziging van de Opiumwet in verband met het toevoegen van een derde lijst met als doel het tegengaan van de productie van en de handel in nieuwe psychoactieve stoffen en enkele andere wijzigingen (Dutch) | year=2024|url=https://www.tweedekamer.nl/kamerstukken/wetsvoorstellen/detail?id=2022Z14042&dossier=36159}}</ref>
 *'''United Kingdom''': NEP is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2010 | url=https://www.legislation.gov.uk/uksi/2010/1207/made}}</ref>
 *'''United States''': NEP is not a controlled substance in the United States but possession or distribution for human use could potentially be prosecuted under the Federal Analogue Act due to its structural and pharmacological similarities to [[pentedrone]].<ref>{{Citation | title=21 U.S. Code § 813 - Treatment of controlled substance analogues | url=https://www.law.cornell.edu/uscode/text/21/813}}</ref>