Methamphetamine: Difference between revisions
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==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
[[File:HarmCausedByDrugsTable.svg|thumb|upright=1.35|Table from the 2010 ISCD study ranking various drugs (legal and illegal) based on statements by drug-harm experts. Methamphetamine was found to be the fourth overall most dangerous drug.<ref name="Nutt_2010">{{cite journal | vauthors = Nutt DJ, King LA, Phillips LD | title = Drug harms in the UK: a multicriteria decision analysis | journal = Lancet | volume = 376 | issue = 9752 | pages = 1558–1565 | date = November 2010 | pmid = 21036393 | doi = 10.1016/S0140-6736(10)61462-6 | s2cid = 5667719 | citeseerx = 10.1.1.690.1283 }}</ref>]] | |||
===Neurotoxicity=== | ===Neurotoxicity=== | ||
There is evidence that methamphetamine causes brain damage from long-term use in humans; this damage includes adverse changes in brain structure and function, such as reductions in gray matter volume in several brain regions and adverse changes in markers of metabolic integrity.<ref>{{cite journal | vauthors=((Nie, L.)), ((Zhao, Z.)), ((Wen, X.)), ((Luo, W.)), ((Ju, T.)), ((Ren, A.)), ((Wu, B.)), ((Li, J.)) | journal=BMC psychiatry | title=Gray-matter structure in long-term abstinent methamphetamine users | volume=20 | issue=1 | pages=158 | date=10 April 2020 | issn=1471-244X | doi=10.1186/s12888-020-02567-3}}</ref> | There is evidence that methamphetamine causes brain damage from long-term use in humans; this damage includes adverse changes in brain structure and function, such as reductions in gray matter volume in several brain regions and adverse changes in markers of metabolic integrity.<ref>{{cite journal | vauthors=((Nie, L.)), ((Zhao, Z.)), ((Wen, X.)), ((Luo, W.)), ((Ju, T.)), ((Ren, A.)), ((Wu, B.)), ((Li, J.)) | journal=BMC psychiatry | title=Gray-matter structure in long-term abstinent methamphetamine users | volume=20 | issue=1 | pages=158 | date=10 April 2020 | issn=1471-244X | doi=10.1186/s12888-020-02567-3}}</ref> |