Pregabalin: Difference between revisions

>Utaninja
I have done extensive research on Pregabalin on behalf of TripSit.me for our current research for additions to the current drug combination chart. I apologize if this formatting is not done properly, was not exactly how to use all these sources best. This also through collaboration of many individuals and I will update if there is more research. You can see more conversation on this topic here: https://github.com/TripSit/drugs/discussions/40
>Utaninja
m fixing typos
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===Seizure Risk===
===Seizure Risk===
Pregabalin has been shown to induce and or increase the risk of seizures at recreational dosages.<ref>https://doi.org/10.1101/cshperspect.a022863</ref><ref>ttps://doi.org/10.1111/j.0013-9580.2004.455003.x</ref><ref>ttps://doi.org/10.1111/j.0013-9580.2004.455003.x</ref><ref>https://doi.org/10.1212/WNL.0000000000000119</ref><ref>https://doi.org/10.1017/S0012162206000843</ref><ref>https://doi.org/10.1097/FAD.0000000000000016</ref><ref>https://doi.org/10.1111/bcp.14348</ref><ref>https://doi.org/10.1111/j.1471-4159.2010.06625.x</ref><ref>https://doi.org/10.1080/24734306.2018.1458465</ref><ref>https://www.reddit.com/r/gabagoodness/comments/111hnbq/had_a_seizure_from_600mg_lyrica_300mg_redose_will/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/z45ypv/i_overdosed_on_pregabalin_and_had_2_really_bad/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/10yos15/how_does_a_seizure_on_pregabalin_looks_like/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/w832w5/what_kind_of_seizures_does_pregabalin_cause/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/115tz8s/pregabalintwitching/</ref><ref>https://www.bluelight.org/community/threads/seizures-from-pregabalin-lyrica.896412/</ref><ref>https://www.erowid.org/experiences/exp.php?ID=69917</ref><ref>https://www.erowid.org/experiences/exp.php?ID=83232</ref><ref>https://www.erowid.org/experiences/exp.php?ID=67302</ref> There is little evidence showing there is a concern at medical dosages (600mg and under). This risk may be increased when mixed with other drugs that lower seizure threshold. Caution is recommended when using doses of higher than 600mg. Reducing various susceptibility factors may also be beneficial in lowering this risk. Susceptibility factors may include things such as low sodium, lack of sleep, and intensive physical activity.
Pregabalin has been shown to induce and or increase the risk of seizures at recreational dosages.<ref>https://doi.org/10.1101/cshperspect.a022863</ref><ref>https://doi.org/10.1111/j.0013-9580.2004.455003.x</ref><ref>https://doi.org/10.1111/j.0013-9580.2004.455003.x</ref><ref>https://doi.org/10.1212/WNL.0000000000000119</ref><ref>https://doi.org/10.1017/S0012162206000843</ref><ref>https://doi.org/10.1097/FAD.0000000000000016</ref><ref>https://doi.org/10.1111/bcp.14348</ref><ref>https://doi.org/10.1111/j.1471-4159.2010.06625.x</ref><ref>https://doi.org/10.1080/24734306.2018.1458465</ref><ref>https://www.reddit.com/r/gabagoodness/comments/111hnbq/had_a_seizure_from_600mg_lyrica_300mg_redose_will/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/z45ypv/i_overdosed_on_pregabalin_and_had_2_really_bad/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/10yos15/how_does_a_seizure_on_pregabalin_looks_like/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/w832w5/what_kind_of_seizures_does_pregabalin_cause/</ref><ref>https://www.reddit.com/r/gabagoodness/comments/115tz8s/pregabalintwitching/</ref><ref>https://www.bluelight.org/community/threads/seizures-from-pregabalin-lyrica.896412/</ref><ref>https://www.erowid.org/experiences/exp.php?ID=69917</ref><ref>https://www.erowid.org/experiences/exp.php?ID=83232</ref><ref>https://www.erowid.org/experiences/exp.php?ID=67302</ref> There is little evidence showing there is a concern at medical dosages (600mg and under). This risk may be increased when mixed with other drugs that lower seizure threshold. Caution is recommended when using doses of higher than 600mg. Reducing various susceptibility factors may also be beneficial in lowering this risk. Susceptibility factors may include things such as low sodium, lack of sleep, and intensive physical activity.


===Lethal dosage===
===Lethal dosage===