Routes of administration: Difference between revisions

>David Hedlund
Oral mucosa
>David Hedlund
sort ====Buccal====
Line 30: Line 30:


===Oral mucosa===
===Oral mucosa===
====Buccal====
[[File:Dipping tobacco in mouth.jpg|thumb|right|[[Dipping tobacco]] is placed directly in the mouth.]]
Buccal administration refers to absorption through the cheek and gum.
This route is commonly employed when ingesting potent psychedelics such as [[25I-NBOMe|25I-NBOMe]], [[DOM]], [[LSD]], and other substances distributed on blotter paper. Potent clandestine manufactured [[benzodiazepines]] like [[alprazolam]] and [[etizolam]] are also sometimes distributed on blotters.
Like sublingual absorption, the substance is largely absorbed through the lingual artery, but is also absorbed through the gum lining. This method is used when chewing plant leaves such as [[khat]], [[kratom]], [[salvia divinorum]], and sometimes [[tobacco]] (snus).


====Sublingual====
====Sublingual====
Line 40: Line 49:
=====Risks=====
=====Risks=====
Caustic compounds, such as the freebase form of amine-containing substance, should not be used sublingually because they can severely burn the inside of one's mouth.
Caustic compounds, such as the freebase form of amine-containing substance, should not be used sublingually because they can severely burn the inside of one's mouth.
====Buccal====
[[File:Dipping tobacco in mouth.jpg|thumb|right|[[Dipping tobacco]] is placed directly in the mouth.]]
Buccal administration refers to absorption through the cheek and gum.
This route is commonly employed when ingesting potent psychedelics such as [[25I-NBOMe|25I-NBOMe]], [[DOM]], [[LSD]], and other substances distributed on blotter paper. Potent clandestine manufactured [[benzodiazepines]] like [[alprazolam]] and [[etizolam]] are also sometimes distributed on blotters.
Like sublingual absorption, the substance is largely absorbed through the lingual artery, but is also absorbed through the gum lining. This method is used when chewing plant leaves such as [[khat]], [[kratom]], [[salvia divinorum]], and sometimes [[tobacco]] (snus).


==Nasal cavity==
==Nasal cavity==