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Safer injection guide: Difference between revisions
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>David Hedlund ===Substances that are dangerous to inject===: Added Codeine |
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* '''Substances''' | * '''Substances''' | ||
** Contraindications | ** Contraindications | ||
*** [[Codeine]] - Injectable codeine is available for subcutaneous or intramuscular injection only; intravenous injection is contraindicated as this can result in non-immune mast-cell degranulation and resulting anaphylactoid reaction. | |||
*** [[Ethchlorvynol]] - Ethchlorvynol is not compatible with intravenous injection and serious injury (including the loss of limbs due to vascular injury) or death can occur when it is used in this manner.<ref>{{cite journal | vauthors = Glauser FL, Smith WR, Caldwell A, Hoshiko M, Dolan GS, Baer H, Olsher N | title = Ethchlorvynol (Placidyl)-induced pulmonary edema | journal = Annals of Internal Medicine | volume = 84 | issue = 1 | pages = 46–8 | date = January 1976 | pmid = 942681 | doi = 10.7326/0003-4819-84-1-46 }}</ref> | *** [[Ethchlorvynol]] - Ethchlorvynol is not compatible with intravenous injection and serious injury (including the loss of limbs due to vascular injury) or death can occur when it is used in this manner.<ref>{{cite journal | vauthors = Glauser FL, Smith WR, Caldwell A, Hoshiko M, Dolan GS, Baer H, Olsher N | title = Ethchlorvynol (Placidyl)-induced pulmonary edema | journal = Annals of Internal Medicine | volume = 84 | issue = 1 | pages = 46–8 | date = January 1976 | pmid = 942681 | doi = 10.7326/0003-4819-84-1-46 }}</ref> | ||
*** [[Hydroxyzine]] (brand name Atarax, and Vistaril) - "The drug is not recommended for {{abbr|SC|subcutaneous}}, {{abbr|IA|intra-articular}}, or {{abbr|SC|subcutaneous}} administration because of adverse reactions that have occurred after its administration via these routes."<ref>{{cite web |title=Hydroxyzine - an overview {{!}} ScienceDirect Topics |url=https://www.sciencedirect.com/topics/neuroscience/hydroxyzine |website=www.sciencedirect.com}}</ref><ref>https://go.drugbank.com/drugs/DB00557</ref><!-- Added to: Routes of administration, Safer injection guide --> | *** [[Hydroxyzine]] (brand name Atarax, and Vistaril) - "The drug is not recommended for {{abbr|SC|subcutaneous}}, {{abbr|IA|intra-articular}}, or {{abbr|SC|subcutaneous}} administration because of adverse reactions that have occurred after its administration via these routes."<ref>{{cite web |title=Hydroxyzine - an overview {{!}} ScienceDirect Topics |url=https://www.sciencedirect.com/topics/neuroscience/hydroxyzine |website=www.sciencedirect.com}}</ref><ref>https://go.drugbank.com/drugs/DB00557</ref><!-- Added to: Routes of administration, Safer injection guide --> | ||