GHB: Difference between revisions

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GHB as the sodium salt, known by the trade name Xyrem,<ref>http://www.reuters.com/finance/stocks/companyProfile?rpc=66&symbol=JAZZ.O</ref> is a prescription sleep-aid which is used to treat various medical conditions such as cataplexy<ref>{{Citation | title=Sodium Oxybate: MedlinePlus Drug Information | url=https://medlineplus.gov/druginfo/meds/a605032.html}}</ref> and excessive daytime sleepiness in patients with narcolepsy.<ref>{{Citation | vauthors=((Kluger, R.)), ((Mamelak, M.)) | title=Pharmaceutical composition and treatment of narcolepsy | url=https://patents.google.com/patent/US4738985A/en}}</ref> It has also been used in a medical setting as a general anesthetic to treat conditions such as insomnia, clinical depression, and alcoholism,<ref>{{Citation | vauthors=((Gessa, G. L.)), ((Fadda, F.)), ((Campochiaro, C. M. di)) | title=Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained | url=https://patents.google.com/patent/US4983632A/en}}</ref> and to improve athletic performance.

GHB is used as a recreational substance for its alcohol-like effects. While a common recreational dose is between 1.5 - 2.5 grams, a dose between 2.5 grams and 5 grams will likely result in falling asleep within 5 - 15 minutes, and a dose of 5 - 10 grams can result in convulsions, unconsciousness (a coma-like state) and vomiting. Doses above 10 grams are associated with a risk of death.<ref name="ErowidGHBVault">{{Citation | title=Erowid GHB Vault : Dosage | url=https://www.erowid.org/chemicals/ghb/ghb_dose.shtml}}</ref> Do not confuse grams with milliliters. If consuming GHB that has already been premixed into a liquid form, additional caution is required as there is no way to know for sure the concentration of the solution (e.g. how many grams of GHB is in each mL of solution). As such, users are advised to start with a low dose and work their way up slowly by increasing the dose in small increments. However, an appropriate interval between dosing is essential to avoid accidental overdose.

GHB is used as a recreational substance for its alcohol-like effects. While a common recreational dose is between 1.5 - 2.5 grams, a dose between 2.5 grams and 5 grams will likely result in falling asleep within 5 - 15 minutes, and a dose of 5 - 10 grams can result in convulsions, unconsciousness (a coma-like state) and vomiting. Doses above 10 grams are associated with a risk of death.<ref name="ErowidGHBVault">{{Citation | title=Erowid GHB Vault : Dosage | url=https://www.erowid.org/chemicals/ghb/ghb_dose.shtml}}</ref> Do not confuse grams with milliliters (the density of GHB is aproximately 1.2g/ml <ref>https://www.chemspider.com/Chemical-Structure.9984.html</ref>). If consuming GHB that has already been premixed into a liquid form, additional caution is required as there is no way to know for sure the concentration of the solution (e.g. how many grams of GHB is in each mL of solution). As such, users are advised to start with a low dose and work their way up slowly by increasing the dose in small increments. However, an appropriate interval between dosing is essential to avoid accidental overdose.

GHB, along with [[GBL]], has acquired a reputation as a "date rape drug," in which it is purportedly secretly placed into alcoholic drinks.{{citation needed}} There is very limited evidence to suggest that this actually happens but care should always be taken when accepting drinks from strangers.

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 GHB as the sodium salt, known by the trade name Xyrem,<ref>http://www.reuters.com/finance/stocks/companyProfile?rpc=66&symbol=JAZZ.O</ref> is a prescription sleep-aid which is used to treat various medical conditions such as cataplexy<ref>{{Citation | title=Sodium Oxybate: MedlinePlus Drug Information | url=https://medlineplus.gov/druginfo/meds/a605032.html}}</ref> and excessive daytime sleepiness in patients with narcolepsy.<ref>{{Citation | vauthors=((Kluger, R.)), ((Mamelak, M.)) | title=Pharmaceutical composition and treatment of narcolepsy | url=https://patents.google.com/patent/US4738985A/en}}</ref> It has also been used in a medical setting as a general anesthetic to treat conditions such as insomnia, clinical depression, and alcoholism,<ref>{{Citation | vauthors=((Gessa, G. L.)), ((Fadda, F.)), ((Campochiaro, C. M. di)) | title=Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained | url=https://patents.google.com/patent/US4983632A/en}}</ref> and to improve athletic performance.
-GHB is used as a recreational substance for its alcohol-like effects. While a common recreational dose is between 1.5 - 2.5 grams, a dose between 2.5 grams and 5 grams will likely result in falling asleep within 5 - 15 minutes, and a dose of 5 - 10 grams can result in convulsions, unconsciousness (a coma-like state) and vomiting. Doses above 10 grams are associated with a risk of death.<ref name="ErowidGHBVault">{{Citation | title=Erowid GHB Vault : Dosage | url=https://www.erowid.org/chemicals/ghb/ghb_dose.shtml}}</ref> Do not confuse grams with milliliters. If consuming GHB that has already been premixed into a liquid form, additional caution is required as there is no way to know for sure the concentration of the solution (e.g. how many grams of GHB is in each mL of solution). As such, users are advised to start with a low dose and work their way up slowly by increasing the dose in small increments. However, an appropriate interval between dosing is essential to avoid accidental overdose.
+GHB is used as a recreational substance for its alcohol-like effects. While a common recreational dose is between 1.5 - 2.5 grams, a dose between 2.5 grams and 5 grams will likely result in falling asleep within 5 - 15 minutes, and a dose of 5 - 10 grams can result in convulsions, unconsciousness (a coma-like state) and vomiting. Doses above 10 grams are associated with a risk of death.<ref name="ErowidGHBVault">{{Citation | title=Erowid GHB Vault : Dosage | url=https://www.erowid.org/chemicals/ghb/ghb_dose.shtml}}</ref> Do not confuse grams with milliliters (the density of GHB is aproximately 1.2g/ml <ref>https://www.chemspider.com/Chemical-Structure.9984.html</ref>). If consuming GHB that has already been premixed into a liquid form, additional caution is required as there is no way to know for sure the concentration of the solution (e.g. how many grams of GHB is in each mL of solution). As such, users are advised to start with a low dose and work their way up slowly by increasing the dose in small increments. However, an appropriate interval between dosing is essential to avoid accidental overdose.
 GHB, along with [[GBL]], has acquired a reputation as a "date rape drug," in which it is purportedly secretly placed into alcoholic drinks.{{citation needed}} There is very limited evidence to suggest that this actually happens but care should always be taken when accepting drinks from strangers.