Piracetam: Difference between revisions

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In the United Kingdom, piracetam is prescribed mainly for myoclonus (spasmodic jerky contraction of groups of muscles),<ref>{{Citation | vauthors=((Henderson, D. R.)) | year=2012 | title=Nootropil (piracetam) | url=http://www.netdoctor.co.uk/medicines/brain-and-nervous-system/news/a7226/nootropil-piracetam/}}</ref> but is used off-label for other conditions. In the United States, it is not approved by the Food and Drug Administration for any medical use and it is not permitted to be sold as a dietary supplement. However, it is still readily available and sold through online vendors. As a "smart drug", it is reported to enhance cognitive functions including memory, intelligence, and attention.<ref>{{Citation | title=Erowid Piracetam Vault : FAQ : Frequently Asked Questions v0.7 | url=https://www.erowid.org/smarts/piracetam/piracetam_faq.shtml}}</ref>

The active dose of piracetam is 100 times than that of [[noopept]],{{citation needed}} making it both the earliest and least potent [[racetam]]. The standard piracetam dose for adults is between 1,200-4,800mg a day. The largest effective dose is 1,600mg taken three times a day for a total of 4,800mg.

The active dose of piracetam is 100 times less than that of [[noopept]],{{citation needed}} making it both the earliest and least potent [[racetam]]. The standard piracetam dose for adults is between 1,200-4,800mg a day. The largest effective dose is 1,600mg taken three times a day for a total of 4,800mg.

==Chemistry==

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The chronic use of piracetam can be considered as [[Addiction potential::not addictive with a low potential for abuse]]. It does not seem to be capable of causing psychological dependence among certain users.

Tolerance to many of the effects of piracetam [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Piracetam may presents cross-tolerance with [[Cross-tolerance::all [[racetam]] [[nootropic]]s]], meaning that after the consumption of piracetam certain [[nootropics]] such as [[aniracetam]] and [[pramiracetam]] may have a reduced effect.

Tolerance to many of the effects of piracetam [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Piracetam may presents cross-tolerance with [[Cross-tolerance::all [[racetam]] [[nootropic]]s]], meaning that after the consumption of piracetam certain [[nootropics]]s such as [[aniracetam]] and [[pramiracetam]] may have a reduced effect.

===Dangerous interactions===

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Piracetam, being a member of the [[racetam]] family, currently is legally available to buy and sell in most countries, but may still vary by region.

*'''Czech Republic:''' Piracetam is not regulated and can be bought in a pharmacy.

*'''Germany:''' Piracetam is a prescription medicine, according to Anlage 1 AMVV.<ref>{{Citation | title=Anlage 1 AMVV - Einzelnorm | url=https://www.gesetze-im-internet.de/amvv/anlage_1.html}}</ref>

*'''Switzerland:''' Piracetam is listed as a "Abgabekategorie B" pharmaceutical, which requires a prescription.{{citation needed}}

@@ Line 9: / Line 9: @@
 In the United Kingdom, piracetam is prescribed mainly for myoclonus (spasmodic jerky contraction of groups of muscles),<ref>{{Citation | vauthors=((Henderson, D. R.)) | year=2012 | title=Nootropil (piracetam) | url=http://www.netdoctor.co.uk/medicines/brain-and-nervous-system/news/a7226/nootropil-piracetam/}}</ref> but is used off-label for other conditions. In the United States, it is not approved by the Food and Drug Administration for any medical use and it is not permitted to be sold as a dietary supplement. However, it is still readily available and sold through online vendors. As a "smart drug", it is reported to enhance cognitive functions including memory, intelligence, and attention.<ref>{{Citation | title=Erowid Piracetam Vault : FAQ : Frequently Asked Questions v0.7 | url=https://www.erowid.org/smarts/piracetam/piracetam_faq.shtml}}</ref>
-The active dose of piracetam is 100 times than that of [[noopept]],{{citation needed}} making it both the earliest and least potent [[racetam]]. The standard piracetam dose for adults is between 1,200-4,800mg a day. The largest effective dose is 1,600mg taken three times a day for a total of 4,800mg.
+The active dose of piracetam is 100 times less than that of [[noopept]],{{citation needed}} making it both the earliest and least potent [[racetam]]. The standard piracetam dose for adults is between 1,200-4,800mg a day. The largest effective dose is 1,600mg taken three times a day for a total of 4,800mg.
 ==Chemistry==
@@ Line 75: / Line 75: @@
 The chronic use of piracetam can be considered as [[Addiction potential::not addictive with a low potential for abuse]]. It does not seem to be capable of causing psychological dependence among certain users.
-Tolerance to many of the effects of piracetam [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Piracetam may presents cross-tolerance with [[Cross-tolerance::all [[racetam]] [[nootropic]]s]], meaning that after the consumption of piracetam certain [[nootropics]] such as [[aniracetam]] and [[pramiracetam]] may have a reduced effect.
+Tolerance to many of the effects of piracetam [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Piracetam may presents cross-tolerance with [[Cross-tolerance::all [[racetam]] [[nootropic]]s]], meaning that after the consumption of piracetam certain [[nootropics]]s such as [[aniracetam]] and [[pramiracetam]] may have a reduced effect.
 ===Dangerous interactions===
@@ Line 84: / Line 84: @@
 Piracetam, being a member of the [[racetam]] family, currently is legally available to buy and sell in most countries, but may still vary by region.
-*'''Czech Republic:''' Piracetam is not regulated and can be bought in a pharmacy.
 *'''Germany:''' Piracetam is a prescription medicine, according to Anlage 1 AMVV.<ref>{{Citation | title=Anlage 1 AMVV - Einzelnorm | url=https://www.gesetze-im-internet.de/amvv/anlage_1.html}}</ref>
 *'''Switzerland:''' Piracetam is listed as a "Abgabekategorie B" pharmaceutical, which requires a prescription.{{citation needed}}