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5-MeO-MiPT: Difference between revisions
>Wombat Rancher Added information on 5-MeO-MiPT's toxicity, added austrian legal status. |
>Wombat Rancher Fixed erroneous citation for austrian legal status, fixed typo. |
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==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}} | {{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}} | ||
Almost nothing is known about the long-term effects of 5-MeO-MiPT. Alongside of this, the exact toxic dosage is unknown | Almost nothing is known about the long-term effects of 5-MeO-MiPT. Alongside of this, the exact toxic dosage is unknown. This is because 5-MeO-MiPT is a [[research chemical]] with very little history of human use. | ||
A preliminary study on mice has shown that a normal dose of 5-MeO-MiPT (0.27 mg/kg) was unable to produce any measurable toxic effects.<ref name=":0">Altuncı YA, Aydoğdu M, Açıkgöz E, Güven Ü, Düzağaç F, Atasoy A, Dağlıoğlu N, Annette Akgür S. [https://pubmed.ncbi.nlm.nih.gov/32936075/ New Psychoactive Substance 5-MeO-MiPT In vivo Acute Toxicity and Hystotoxicological Study.] Balkan Med J. 2021 Jan;38(1):34-42. [[wikipedia:Digital_object_identifier|doi]]:[https://doi.org/10.4274/balkanmedj.galenos.2020.2019.11.68 10.4274/balkanmedj.galenos.2020.2019.11.68] [[wikipedia:PubMed_Identifier|PMID]]: [https://pubmed.ncbi.nlm.nih.gov/32936075/ 32936075]; [https://en.wikipedia.org/wiki/PubMed_Central#PMCID PMCID]: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8909217/ PMC8909217]. | A preliminary study on mice has shown that a normal dose of 5-MeO-MiPT (0.27 mg/kg) was unable to produce any measurable toxic effects.<ref name=":0">Altuncı YA, Aydoğdu M, Açıkgöz E, Güven Ü, Düzağaç F, Atasoy A, Dağlıoğlu N, Annette Akgür S. [https://pubmed.ncbi.nlm.nih.gov/32936075/ New Psychoactive Substance 5-MeO-MiPT In vivo Acute Toxicity and Hystotoxicological Study.] Balkan Med J. 2021 Jan;38(1):34-42. [[wikipedia:Digital_object_identifier|doi]]:[https://doi.org/10.4274/balkanmedj.galenos.2020.2019.11.68 10.4274/balkanmedj.galenos.2020.2019.11.68] [[wikipedia:PubMed_Identifier|PMID]]: [https://pubmed.ncbi.nlm.nih.gov/32936075/ 32936075]; [https://en.wikipedia.org/wiki/PubMed_Central#PMCID PMCID]: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8909217/ PMC8909217]. | ||
<br /></ref> However, doses of 5-MeO-MiPT way above the normal dosage range (2.7 mg/kg) have been shown to produce cell toxicity by triggering programmed cell death in the brain, liver and kidneys. The extent of the damage, if it occurs in other bodily tissues as well and how it is caused is not known yet. | <br /></ref> However, doses of 5-MeO-MiPT way above the normal dosage range (2.7 mg/kg) have been shown to produce cell toxicity by triggering programmed cell death in the brain, liver and kidneys. The extent of the damage, if it occurs in other bodily tissues as well and how it is caused is not known yet. | ||
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==Legal status== | ==Legal status== | ||
*'''Austria''': 5-MeO-MiPT is illegal to possess, produce and sell under the NPSG (''Neue Psychoaktive Substanzen Gesetz'').<ref | *'''Austria''': 5-MeO-MiPT is illegal to possess, produce and sell under the NPSG (''Neue Psychoaktive Substanzen Gesetz'').<ref>[https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=20007605 Gesamte Rechtsvorschrift für Neue-Psychoaktive-Substanzen-Gesetz] ''(in german). Bundeskriminalamt Österreich. Retrieved April 13, 2023.''</ref> However, offenders with no intent to distribute will likely not have to face prosecution. | ||
*'''Brazil''': 5-MeO-MiPT is illegal to produce, sell, or possess as it is listed on Portaria SVS/MS nº 344.<ref>{{cite web|url=http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7|title=RESOLUÇÃO DA DIRETORIA COLEGIADA - RDC N° 130, DE 2 DE DEZEMBRO DE 2016|publication-date=December 5, 2016|publisher=Agência Nacional de Vigilância Sanitária (ANVISA) [Brazilian Health Regulatory Agency (ANVISA)]|language=pt}}</ref> | *'''Brazil''': 5-MeO-MiPT is illegal to produce, sell, or possess as it is listed on Portaria SVS/MS nº 344.<ref>{{cite web|url=http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7|title=RESOLUÇÃO DA DIRETORIA COLEGIADA - RDC N° 130, DE 2 DE DEZEMBRO DE 2016|publication-date=December 5, 2016|publisher=Agência Nacional de Vigilância Sanitária (ANVISA) [Brazilian Health Regulatory Agency (ANVISA)]|language=pt}}</ref> | ||
*'''China''': 5-MeO-MiPT is controlled as a Category I psychotropic substance and is illegal to sell, buy, import, export, and manufacture.<ref>{{cite web|title=Erowid China Psychoactive Law Update: September 2015|url=https://www.erowid.org/psychoactives/law/countries/china/china_law_2015_09_27_list_of_newly_controlled_chemicals.pdf|access-date=September 29, 2020|publisher=Erowid}}</ref> | *'''China''': 5-MeO-MiPT is controlled as a Category I psychotropic substance and is illegal to sell, buy, import, export, and manufacture.<ref>{{cite web|title=Erowid China Psychoactive Law Update: September 2015|url=https://www.erowid.org/psychoactives/law/countries/china/china_law_2015_09_27_list_of_newly_controlled_chemicals.pdf|access-date=September 29, 2020|publisher=Erowid}}</ref> | ||