This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Selective serotonin reuptake inhibitor: Difference between revisions
>Rieslikesopiates mNo edit summary |
>DecreasinglyDocile No edit summary |
||
| Line 19: | Line 19: | ||
*'''[[Effect::Physical fatigue]]''' | *'''[[Effect::Physical fatigue]]''' | ||
*'''[[Effect::Appetite enhancement]]''' ''or'' '''[[Effect::appetite suppression]]''' | *'''[[Effect::Appetite enhancement]]''' ''or'' '''[[Effect::appetite suppression]]''' | ||
*'''[[Effect::Decreased libido]]''' - | *'''[[Effect::Decreased libido]]''' - Decreased libido and sexual dysfunction are among the most commonly reported side effects of SSRIs. In some cases these effects may persist after use is discontinued, this is known as PSSD.<ref>{{cite web|author=Pharmacovigilance Risk Assessment Committee (PRAC)|date=11 June 2019|title=New product information wording – Extracts from PRAC recommendations on signals|url=https://www.ema.europa.eu/en/documents/other/new-product-information-wording-extracts-prac-recommendations-signals-adopted-13-16-may-2019-prac_en.pdf#page=2|publisher=European Medicines Agency|id=EMA/PRAC/265221/2019}}</ref> On the other hand, suppression of depression may enhance libido. | ||
*'''[[Effect::Orgasm suppression]]''' - This effect is usually mild and only delays orgasms, however in some people, particularly older users, SSRIs can make one completely unable to reach orgasm. This is usually treated by either switching to a different antidepressant, or adding a DNRI such as [[bupropion]]. Short-acting SSRIs such as dapoxetine are approved drugs for premature ejaculation. | *'''[[Effect::Orgasm suppression]]''' - This effect is usually mild and only delays orgasms, however in some people, particularly older users, SSRIs can make one completely unable to reach orgasm. This is usually treated by either switching to a different antidepressant, or adding a DNRI such as [[bupropion]]. Short-acting SSRIs such as dapoxetine are approved drugs for premature ejaculation. | ||
*'''[[Effect::Pain relief]]''' - Some studies suggest they can be effective as analgesics (painkillers).<ref>https://www.med.unc.edu/ibs/files/2017/10/IBS-and-Antidepressants.pdf</ref> | *'''[[Effect::Pain relief]]''' - Some studies suggest they can be effective as analgesics (painkillers).<ref>https://www.med.unc.edu/ibs/files/2017/10/IBS-and-Antidepressants.pdf</ref> | ||
| Line 28: | Line 28: | ||
*'''[[Effect::Dry mouth]]''' | *'''[[Effect::Dry mouth]]''' | ||
*'''[[Effect::Vasoconstriction]]'''{{citation needed}} | *'''[[Effect::Vasoconstriction]]'''{{citation needed}} | ||
}}|{{effects/visual| | }} | ||
|{{effects/visual| | |||
SSRIs are capable of inconsistently inducing changes in visual perception - often during the beginning of treatment. | SSRIs are capable of inconsistently inducing changes in visual perception - often during the beginning of treatment. | ||
| Line 44: | Line 46: | ||
}} | }} | ||
{{effects/cognitive| | {{effects/cognitive| | ||
*'''[[Effect:: | *'''[[Effect::Apathy]]'''<ref>{{cite journal |last1=Barnhart |first1=WJ |last2=Makela |first2=EH |last3=Latocha |first3=MJ |title=SSRI-induced apathy syndrome: a clinical review. |journal=Journal of psychiatric practice |date=May 2004 |volume=10 |issue=3 |pages=196-9 |doi=10.1097/00131746-200405000-00010 |pmid=15330228}}</ref> | ||
*'''[[Effect::Motivation suppression]] or [[Effect::Motivation enhancement]]''' - Lack of motivation is anecdotally reported with SSRIs, though on the other hand, suppression of depression or anxiety may enhance motivation. | |||
*'''[[Effect::Anxiety suppression]]''' | *'''[[Effect::Anxiety suppression]]''' | ||
*'''[[Effect::Cognitive fatigue]]''' | *'''[[Effect::Cognitive fatigue]]''' | ||
| Line 53: | Line 56: | ||
*'''[[Effect::Emotion enhancement]]''' - Upon first introduction, some users can experience amplified emotions. | *'''[[Effect::Emotion enhancement]]''' - Upon first introduction, some users can experience amplified emotions. | ||
*'''[[Effect::Mania]]''' | *'''[[Effect::Mania]]''' | ||
}} | }} | ||
{{effects/paradoxical| | {{effects/paradoxical| | ||