Safer injection guide: Difference between revisions

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! Properties !! European Pharmacopoeia (Ph.Eur.)<ref>{{cite book|title=European Pharmacopoeia|date=2013|publisher=Council of Europe|location=Strasbourg, France|isbn=978-92-871-7531-1|pages=3555–3558|edition=8|language=English|chapter=Water for injections}}</ref> !! United States Pharmacopeia (USP)<ref>{{cite book|title=United States Pharmacopeia and the National Formulary (USP-NF)|date=October 2014|publisher=U.S. Pharmacopeial Convention|location=Rockville, MD, USA|page=5805|edition=USP38–NF33|chapter=USP Monographs: Water for Injection}}</ref>

|-

| Conductivity~~<ref group=upper-alpha>If in-line conductivity exceeds values additional testing is required before a conclusion can be made. Refer to the respective pharmacopoeia for details.</ref>~~ || <1.3 μS/cm at 25 °C||<1.3 μS/cm at 25 °C

| Conductivity[1] || <1.3 μS/cm at 25 °C||<1.3 μS/cm at 25 °C

|-

| Total organic carbon (TOC) || <0.5 mg/L || <0.50 mg/L

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| Bacteria (guideline) || <10 {{abbr|CFU|colony forming units}}/100 mL || <10 {{abbr|CFU|colony forming units}}/100 mL

|-

| Endotoxin || <0.25 IU/mL || <0.25 EU/mL ~~<ref group=upper-alpha>One USP Endotoxin Unit (EU) is equal to one International Unit (IU) of endotoxin</ref>~~

| Endotoxin || <0.25 IU/mL || <0.25 EU/mL[2]

|-

| Nitrates || <0.2 ppm || N/A

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| Aluminium || <10 ppb || N/A

|}

# If in-line conductivity exceeds values additional testing is required before a conclusion can be made. Refer to the respective pharmacopoeia for details.

# One USP Endotoxin Unit (EU) is equal to one International Unit (IU) of endotoxin

* [https://en.wikipedia.org/wiki/Eye_drop Eye drops]

@@ Line 85: / Line 85: @@
 ! Properties !! European Pharmacopoeia (Ph.Eur.)<ref>{{cite book|title=European Pharmacopoeia|date=2013|publisher=Council of Europe|location=Strasbourg, France|isbn=978-92-871-7531-1|pages=3555–3558|edition=8|language=English|chapter=Water for injections}}</ref> !! United States Pharmacopeia (USP)<ref>{{cite book|title=United States Pharmacopeia and the National Formulary (USP-NF)|date=October 2014|publisher=U.S. Pharmacopeial Convention|location=Rockville, MD, USA|page=5805|edition=USP38–NF33|chapter=USP Monographs: Water for Injection}}</ref>
 |-
-| Conductivity<ref group=upper-alpha>If in-line conductivity exceeds values additional testing is required before a conclusion can be made. Refer to the respective pharmacopoeia for details.</ref> || <1.3 μS/cm at 25&nbsp;°C||<1.3 μS/cm at 25&nbsp;°C
+| Conductivity[1] || <1.3 μS/cm at 25&nbsp;°C||<1.3 μS/cm at 25&nbsp;°C
 |-
 | Total organic carbon (TOC) || <0.5&nbsp;mg/L || <0.50&nbsp;mg/L
@@ Line 91: / Line 91: @@
 | Bacteria (guideline) || <10 {{abbr|CFU|colony forming units}}/100 mL || <10 {{abbr|CFU|colony forming units}}/100 mL
 |-
-| Endotoxin || <0.25 IU/mL || <0.25 EU/mL <ref group=upper-alpha>One USP Endotoxin Unit (EU) is equal to one International Unit (IU) of endotoxin</ref>
+| Endotoxin || <0.25 IU/mL || <0.25 EU/mL[2]
 |-
 | Nitrates || <0.2 ppm || N/A
@@ Line 97: / Line 97: @@
 | Aluminium || <10 ppb || N/A
 |}
+# If in-line conductivity exceeds values additional testing is required before a conclusion can be made. Refer to the respective pharmacopoeia for details.
+# One USP Endotoxin Unit (EU) is equal to one International Unit (IU) of endotoxin
 * [https://en.wikipedia.org/wiki/Eye_drop Eye drops]