2C-P: Difference between revisions

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2C-P is a relatively potent and long acting psychedelic phenethylamine of the 2C family which possesses stimulant type effects as well. It was first described by Alexander Shulgin in his book ''[[PiHKAL]]''.

~~Pharmacokinetic factors that make 2C-P pretty unique and require notably caution:~~

* Steep dose-response curve: As little as a few extra milligrams separating a manageable dose and an overdose.<ref name="Erowid" />

* Very slow onset: The peak effects reportedly do not occur for 1 to 3 hours.<ref name="Erowid">{{Citation | title=Erowid Online Books : “PIHKAL” - #36 2C-P | url=https://www.erowid.org/library/books_online/pihkal/pihkal036.shtml}}</ref>

* Long half-life: The anecdotal estimated elimination half-life is 19 hours.<ref>https://pubmed.ncbi.nlm.nih.gov/28130544/</ref>

2C-P has been shown to produce a variety of intense [[hallucinogenic]] type effects ranging from drastic changes in consciousness and perception, to open and closed eye visuals. 2C-P is considered to be one of the strongest 2C-x compounds dosage for dosage, rivaled only by 2C-TFM.

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===Overdose===

The LD<sub>50</sub> of 2C-P has not been established. However, it is believed that 2C-P is likely to have a smaller therapeutic window compared to other 2C's, meaning a lethal dose may be achieved more easily. 2C-P is known to be highly dose-sensitive: a difference of 2 or 5 milligrams may radically change the nature of the experience along with its safety profile. Users who wish to take high doses of this compound are advised to titrate upward slowly, use reliable milligram scales to measure doses, and avoid non-oral routes of administration such as insufflation or injection.

Pharmacokinetic factors that make 2C-P pretty unique and require notably caution:

* Steep dose-response curve: As little as a few extra milligrams separating a manageable dose and an overdose.<ref name="Erowid" /> Users who wish to take high doses of this compound are advised to titrate upward slowly, use reliable milligram scales to measure doses, and avoid non-oral routes of administration such as insufflation or injection.

* Very slow onset: The peak effects reportedly do not occur for 1 to 3 hours.<ref name="Erowid">{{Citation | title=Erowid Online Books : “PIHKAL” - #36 2C-P | url=https://www.erowid.org/library/books_online/pihkal/pihkal036.shtml}}</ref> Thus it's advised to wait for at least 3 hours before re-dosing is considered.

* Long half-life: The anecdotal estimated elimination half-life is 19 hours.<ref>https://pubmed.ncbi.nlm.nih.gov/28130544/</ref>

The LD<sub>50</sub> of 2C-P has not been established. However, it is believed that 2C-P is likely to have a smaller therapeutic window compared to other 2C's, meaning a lethal dose may be achieved more easily.

In 2017, a 25-year old British female died following the ingestion of a large dose of 2C-P at a music festival.<ref>{{cite news|author=Steven Morris|date=February 13, 2019|title=Bestival death may be world's first 2C-P fatality, court hears|url=https://www.theguardian.com/uk-news/2019/feb/13/bestival-death-may-be-worlds-first-2-cp-fatality-court-hears|publisher=The Guardian|access-date=October 12, 2020}}</ref> No source reported clear evidence that 2C-P by itself led to the immediate death of the female.

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 {{Further|Serotonergic psychedelic}}
 C-P is a relatively potent and long acting psychedelic phenethylamine of the 2C family which possesses stimulant type effects as well. It was first described by Alexander Shulgin in his book ''[[PiHKAL]]''.
-Pharmacokinetic factors that make 2C-P pretty unique and require notably caution:
-* Steep dose-response curve: As little as a few extra milligrams separating a manageable dose and an overdose.<ref name="Erowid" />
-* Very slow onset: The peak effects reportedly do not occur for 1 to 3 hours.<ref name="Erowid">{{Citation | title=Erowid Online Books : “PIHKAL” - #36 2C-P | url=https://www.erowid.org/library/books_online/pihkal/pihkal036.shtml}}</ref>
-* Long half-life: The anecdotal estimated elimination half-life is 19 hours.<ref>https://pubmed.ncbi.nlm.nih.gov/28130544/</ref>
 C-P has been shown to produce a variety of intense [[hallucinogenic]] type effects ranging from drastic changes in consciousness and perception, to open and closed eye visuals. 2C-P is considered to be one of the strongest 2C-x compounds dosage for dosage, rivaled only by 2C-TFM.
@@ Line 127: / Line 122: @@
 ===Overdose===
-The LD<sub>50</sub> of 2C-P has not been established. However, it is believed that 2C-P is likely to have a smaller therapeutic window compared to other 2C's, meaning a lethal dose may be achieved more easily. 2C-P is known to be highly dose-sensitive: a difference of 2 or 5 milligrams may radically change the nature of the experience along with its safety profile. Users who wish to take high doses of this compound are advised to titrate upward slowly, use reliable milligram scales to measure doses, and avoid non-oral routes of administration such as insufflation or injection.
+Pharmacokinetic factors that make 2C-P pretty unique and require notably caution:
+* Steep dose-response curve: As little as a few extra milligrams separating a manageable dose and an overdose.<ref name="Erowid" /> Users who wish to take high doses of this compound are advised to titrate upward slowly, use reliable milligram scales to measure doses, and avoid non-oral routes of administration such as insufflation or injection.
+* Very slow onset: The peak effects reportedly do not occur for 1 to 3 hours.<ref name="Erowid">{{Citation | title=Erowid Online Books : “PIHKAL” - #36 2C-P | url=https://www.erowid.org/library/books_online/pihkal/pihkal036.shtml}}</ref> Thus it's advised to wait for at least 3 hours before re-dosing is considered.
+* Long half-life: The anecdotal estimated elimination half-life is 19 hours.<ref>https://pubmed.ncbi.nlm.nih.gov/28130544/</ref>
+The LD<sub>50</sub> of 2C-P has not been established. However, it is believed that 2C-P is likely to have a smaller therapeutic window compared to other 2C's, meaning a lethal dose may be achieved more easily.
 In 2017, a 25-year old British female died following the ingestion of a large dose of 2C-P at a music festival.<ref>{{cite news|author=Steven Morris|date=February 13, 2019|title=Bestival death may be world's first 2C-P fatality, court hears|url=https://www.theguardian.com/uk-news/2019/feb/13/bestival-death-may-be-worlds-first-2-cp-fatality-court-hears|publisher=The Guardian|access-date=October 12, 2020}}</ref> No source reported clear evidence that 2C-P by itself led to the immediate death of the female.