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Unique substance warnings: Difference between revisions
>David Hedlund Gathered unique substance warnings that I've collected (added to the linked pages) through the years. This should make it easy for Isaak to add warning messages to specific substances in PsychonautWiki Journal. |
>David Hedlund →Psychoactive substances: * DXM: "It should be noted that DXM in freebase form (as found in Robocough RoboTablets) is around 27-37% more potent than its hydrobromide form..." -- copy/pasted text from the DXM article |
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* [[MAOI]]s: Tyramine causes hypertensive crises after MAO inhibition aka the "cheese effect" or "cheese crisis". Using a MAO inhibitor (MAOI), the intake of approximately 10 to 25 mg of tyramine is required for a severe reaction compared to 6 to 10 mg for a mild reaction. Tyramine rich food should also be avoided by people prone to headache and migraine. Stilton (a blue cheese) contains up to 217 mg tyramine per 100 grams. - https://www.mc.vanderbilt.edu/documents/neurology/files/Tyramine%20Menu%20Book%2006227101.pdf | * [[MAOI]]s: Tyramine causes hypertensive crises after MAO inhibition aka the "cheese effect" or "cheese crisis". Using a MAO inhibitor (MAOI), the intake of approximately 10 to 25 mg of tyramine is required for a severe reaction compared to 6 to 10 mg for a mild reaction. Tyramine rich food should also be avoided by people prone to headache and migraine. Stilton (a blue cheese) contains up to 217 mg tyramine per 100 grams. - https://www.mc.vanderbilt.edu/documents/neurology/files/Tyramine%20Menu%20Book%2006227101.pdf | ||
* Psilocybin mushrooms: x mg psilocybin is stored in each fully developed fruit body. So the number of species is more relevant than the quantity. | * Psilocybin mushrooms: x mg psilocybin is stored in each fully developed fruit body. So the number of species is more relevant than the quantity. | ||
===Chemical forms=== | |||
* [[DXM]]: "It should be noted that DXM in freebase form (as found in Robocough RoboTablets) is around 27-37% more potent than its hydrobromide form due to a higher concentration of DXM by weight. One should take this into account when calculating their dose so as to avoid a potential overdose." | |||
===[[Dosage]]=== | ===[[Dosage]]=== | ||
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===Genotype=== | ===Genotype=== | ||
* [[THC]]: ''CYP2C9'' genotype affects THC sensitivity significantly: ''Subjects with the *3/*3 genotype had 3-fold higher THC levels in their blood than subjects with the *1/*1 genotype. Those subjects with one copy of each gene (*1/*3) had intermediate THC levels that were about 2-fold higher than subjects with *1/*1.''<ref>https://www.ncbi.nlm.nih.gov/books/NBK564166/</ref> | * [[THC]]: ''CYP2C9'' genotype affects THC sensitivity significantly: ''Subjects with the *3/*3 genotype had 3-fold higher THC levels in their blood than subjects with the *1/*1 genotype. Those subjects with one copy of each gene (*1/*3) had intermediate THC levels that were about 2-fold higher than subjects with *1/*1.''<ref>https://www.ncbi.nlm.nih.gov/books/NBK564166/</ref> | ||
==References== | ==References== | ||
{{reflist}} | {{reflist}} | ||