Lisdexamfetamine: Difference between revisions

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{{SummarySheet}}
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{{SubstanceBox/Lisdexamfetamine}}
{{SubstanceBox/Lisdexamfetamine}}
'''Lisdexamfetamine''' (also known as '''lisdextroamphetamine''', '''L-lysine-dextroamphetamine''', or '''lisdexamfetamine dimesylate''' when under the brand names '''Elvanse''' and '''Vyvanse''') is a [[psychoactive class::stimulant]] substance of the [[chemical class::amphetamine]] class. It is a "mutual [[prodrug]]" ([https://en.wikipedia.org/wiki/Codrug codrug]) for [[Amphetamine#Enantiomers|<small>d</small>-amphetamine]] (dextroamphetamine) that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge-eating disorder.<ref>https://www.drugs.com/pro/vyvanse.html</ref> Like amphetamine, lisdexamfetamine produces its effects by promoting the release of [[neurotransmitters]] [[dopamine]] and [[norepinephrine]] in the brain.
'''Lisdexamfetamine''' (also known as '''lisdextroamphetamine''', '''L-lysine-dextroamphetamine''', or '''lisdexamfetamine dimesylate''' when under the brand names '''Elvanse''', '''Tyvense''', and '''Vyvanse''') is a [[psychoactive class::stimulant]] substance of the [[chemical class::amphetamine]] class. It is a "mutual [[prodrug]]" ([https://en.wikipedia.org/wiki/Codrug codrug]) for [[Amphetamine#Enantiomers|<small>d</small>-amphetamine]] (dextroamphetamine) that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge-eating disorder.<ref>https://www.drugs.com/pro/vyvanse.html</ref> Like amphetamine, lisdexamfetamine produces its effects by promoting the release of [[neurotransmitters]] [[dopamine]] and [[norepinephrine]] in the brain.


[[Subjective effects]] are essentially identical to that of dextroamphetamine except with a slower onset and a longer duration. These include [[stimulation]], [[focus enhancement]], [[motivation enhancement]], and [[euphoria]]. However, unlike dextroamphetamine, lisdexamfetamine was specifically designed to prevent non-oral forms of administration (marketed as an anti-abuse design). This means that [[insufflation]], [[Route of administration#Smoked|smoking]] or [[Route of administration#Injection|injection]] do not provide faster absorption or onset. It is sometimes sold and used illicitly as a "study drug" as well as a recreational substance.  
[[Subjective effects]] are essentially identical to that of dextroamphetamine except with a slower onset and a longer duration. These include [[stimulation]], [[focus enhancement]], [[motivation enhancement]], and [[euphoria]]. However, unlike dextroamphetamine, lisdexamfetamine was specifically designed to prevent non-oral forms of administration (marketed as an anti-abuse design). This means that [[insufflation]], [[Route of administration#Smoked|smoking]] or [[Route of administration#Injection|injection]] do not provide faster absorption or onset. It is sometimes sold and used illicitly as a "study drug" as well as a recreational substance.