Selective serotonin reuptake inhibitor: Difference between revisions

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===Fluoxetine===

Fluoxetine is an SSRI commonly sold under the brand name '''Prozac'''. Fluoxetine is indicated for the treatment of major depressive disorder, bulimia nervosa, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder. Fluoxetine is sometimes used in conjunction with olanzapine (an atypical antipsychotic) to treat bipolar I disorder as well as treatment-resistant depression.<ref>Fluoxetine | https://www.drugs.com/fluoxetine.html</ref>A single pill medication called '''Symbyax''' is a combination of olanzapine and fluoxetine.<ref>Symbyax Prescribing Information | http://pi.lilly.com/us/symbyax-pi.pdf</ref>Fluoxetine is on the World Health Organization's list of essential medicines, a list of medicines needed for a basic and effective health system.<ref>WHO List of Essential Medicines | http://www.who.int/medicines/publications/essentialmedicines/EML2015_8-May-15.pdf</ref>Fluoxetine was first FDA approved in 1987.

Fluoxetine is an SSRI commonly sold under the brand name '''Prozac'''. Fluoxetine is indicated for the treatment of major depressive disorder, bulimia nervosa, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder. Fluoxetine is sometimes used in conjunction with olanzapine (an atypical antipsychotic) to treat bipolar I disorder as well as treatment-resistant depression.<ref>Fluoxetine | https://www.drugs.com/fluoxetine.html</ref>A single pill medication called '''Symbyax''' is a combination of olanzapine and fluoxetine.<ref>Symbyax Prescribing Information | http://pi.lilly.com/us/symbyax-pi.pdf</ref> Fluoxetine is on the World Health Organization's list of essential medicines, a list of medicines needed for a basic and effective health system.<ref>WHO List of Essential Medicines | http://www.who.int/medicines/publications/essentialmedicines/EML2015_8-May-15.pdf</ref> Fluoxetine was first FDA approved in 1987.

===Fluvoxamine===

Fluvoxamine is an SSRI that is used to treat obsessive-compulsive disorder. Fluvoxamine was first approved by the FDA in 1994.<ref>Fluvoxamine | https://www.drugs.com/cdi/fluvoxamine.html</ref>Fluvoxamine has the greatest affinity for the σ1 (sigma-1) receptor, where it acts as an [[agonist]], which may contribute to its biological effects.<ref>{{cite journal | vauthors=((Hashimoto, K.)) | journal=Central Nervous System Agents in Medicinal Chemistry | title=Sigma-1 receptors and selective serotonin reuptake inhibitors: clinical implications of their relationship | volume=9 | issue=3 | pages=197–204 | date= September 2009 | issn=1875-6166 | doi=10.2174/1871524910909030197}}</ref>

Fluvoxamine is an SSRI that is used to treat obsessive-compulsive disorder. Fluvoxamine was first approved by the FDA in 1994.<ref>Fluvoxamine | https://www.drugs.com/cdi/fluvoxamine.html</ref> Fluvoxamine has the greatest affinity for the σ1 (sigma-1) receptor, where it acts as an [[agonist]], which may contribute to its biological effects.<ref>{{cite journal | vauthors=((Hashimoto, K.)) | journal=Central Nervous System Agents in Medicinal Chemistry | title=Sigma-1 receptors and selective serotonin reuptake inhibitors: clinical implications of their relationship | volume=9 | issue=3 | pages=197–204 | date= September 2009 | issn=1875-6166 | doi=10.2174/1871524910909030197}}</ref>

===Paroxetine===

@@ Line 92: / Line 92: @@
 ===Fluoxetine===
-Fluoxetine is an SSRI commonly sold under the brand name '''Prozac'''. Fluoxetine is indicated for the treatment of major depressive disorder, bulimia nervosa, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder. Fluoxetine is sometimes used in conjunction with olanzapine (an atypical antipsychotic) to treat bipolar I disorder as well as treatment-resistant depression.<ref>Fluoxetine | https://www.drugs.com/fluoxetine.html</ref>A single pill medication called '''Symbyax''' is a combination of olanzapine and fluoxetine.<ref>Symbyax Prescribing Information | http://pi.lilly.com/us/symbyax-pi.pdf</ref>Fluoxetine is on the World Health Organization's list of essential medicines, a list of medicines needed for a basic and effective health system.<ref>WHO List of Essential Medicines | http://www.who.int/medicines/publications/essentialmedicines/EML2015_8-May-15.pdf</ref>Fluoxetine was first FDA approved in 1987.
+Fluoxetine is an SSRI commonly sold under the brand name '''Prozac'''. Fluoxetine is indicated for the treatment of major depressive disorder, bulimia nervosa, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder. Fluoxetine is sometimes used in conjunction with olanzapine (an atypical antipsychotic) to treat bipolar I disorder as well as treatment-resistant depression.<ref>Fluoxetine | https://www.drugs.com/fluoxetine.html</ref>A single pill medication called '''Symbyax''' is a combination of olanzapine and fluoxetine.<ref>Symbyax Prescribing Information | http://pi.lilly.com/us/symbyax-pi.pdf</ref> Fluoxetine is on the World Health Organization's list of essential medicines, a list of medicines needed for a basic and effective health system.<ref>WHO List of Essential Medicines | http://www.who.int/medicines/publications/essentialmedicines/EML2015_8-May-15.pdf</ref> Fluoxetine was first FDA approved in 1987.
 ===Fluvoxamine===
-Fluvoxamine is an SSRI that is used to treat obsessive-compulsive disorder. Fluvoxamine was first approved by the FDA in 1994.<ref>Fluvoxamine | https://www.drugs.com/cdi/fluvoxamine.html</ref>Fluvoxamine has the greatest affinity for the σ1 (sigma-1) receptor, where it acts as an [[agonist]], which may contribute to its biological effects.<ref>{{cite journal | vauthors=((Hashimoto, K.)) | journal=Central Nervous System Agents in Medicinal Chemistry | title=Sigma-1 receptors and selective serotonin reuptake inhibitors: clinical implications of their relationship | volume=9 | issue=3 | pages=197–204 | date= September 2009 | issn=1875-6166 | doi=10.2174/1871524910909030197}}</ref>
+Fluvoxamine is an SSRI that is used to treat obsessive-compulsive disorder. Fluvoxamine was first approved by the FDA in 1994.<ref>Fluvoxamine | https://www.drugs.com/cdi/fluvoxamine.html</ref> Fluvoxamine has the greatest affinity for the σ1 (sigma-1) receptor, where it acts as an [[agonist]], which may contribute to its biological effects.<ref>{{cite journal | vauthors=((Hashimoto, K.)) | journal=Central Nervous System Agents in Medicinal Chemistry | title=Sigma-1 receptors and selective serotonin reuptake inhibitors: clinical implications of their relationship | volume=9 | issue=3 | pages=197–204 | date= September 2009 | issn=1875-6166 | doi=10.2174/1871524910909030197}}</ref>
 ===Paroxetine===