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Pregabalin: Difference between revisions
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>Khalil1011 →Subjective effects: Added tactile suppression, and updated motor control loss/tactile enchantment and seizures. |
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*'''[[Effect::Spontaneous bodily sensations]]''' - The general "body high" of pregabalin can be described as a sharp, pleasurable tingling sensation which is location specific to the hands, feet, and head. | *'''[[Effect::Spontaneous bodily sensations]]''' - The general "body high" of pregabalin can be described as a sharp, pleasurable tingling sensation which is location specific to the hands, feet, and head. | ||
*'''[[Effect::Physical euphoria]]''' - This component, while prominent in the experience, is generally not as strong as the cognitive euphoria that can be induced. The sensation itself can be described as feelings of physical comfort, warmth and bliss. | *'''[[Effect::Physical euphoria]]''' - This component, while prominent in the experience, is generally not as strong as the cognitive euphoria that can be induced. The sensation itself can be described as feelings of physical comfort, warmth and bliss. | ||
*'''[[Effect::Tactile enhancement]]''' | *'''[[Effect::Tactile enhancement]]''' - Although the user’s body may feel numb, the sense of touch can be heightened at the same time. | ||
*'''[[Effect::Muscle twitching]]''' - Somewhat paradoxically, since pregabalin is used as an adjunct treatment for epilepsy, pregabalin, especially in higher doses, can produce muscle spasms.{{citation needed}} Anecdotally, seizures have been reported in overdose.{{citation needed}} | *'''[[Effect::Muscle twitching]]''' - Somewhat paradoxically, since pregabalin is used as an adjunct treatment for epilepsy, pregabalin, especially in higher doses, can produce muscle spasms.{{citation needed}} Anecdotally, seizures have been reported in overdose.{{citation needed}} | ||
*'''[[Effect::Respiratory depression]]''' - While pregabalin may cause respiratory depression, this effect is not as strong as those with [[opioids]] and [[benzodiazepines]].<ref>{{cite journal | vauthors=((Eipe, N.)), ((Penning, J.)) | journal=Pain Research & Management : The Journal of the Canadian Pain Society | title=Postoperative respiratory depression associated with pregabalin: A case series and a preoperative decision algorithm | volume=16 | issue=5 | pages=353–356 | date= 2011 | url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206785/ | issn=1203-6765}}</ref> | *'''[[Effect::Respiratory depression]]''' - While pregabalin may cause respiratory depression, this effect is not as strong as those with [[opioids]] and [[benzodiazepines]].<ref>{{cite journal | vauthors=((Eipe, N.)), ((Penning, J.)) | journal=Pain Research & Management : The Journal of the Canadian Pain Society | title=Postoperative respiratory depression associated with pregabalin: A case series and a preoperative decision algorithm | volume=16 | issue=5 | pages=353–356 | date= 2011 | url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206785/ | issn=1203-6765}}</ref> | ||
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*'''[[Effect::Perception of bodily lightness]]''' - At very high doses, some users report feeling lighter. | *'''[[Effect::Perception of bodily lightness]]''' - At very high doses, some users report feeling lighter. | ||
*'''[[Effect::Increased libido]]''' ''or'' '''[[Effect::Decreased libido]]''' | *'''[[Effect::Increased libido]]''' ''or'' '''[[Effect::Decreased libido]]''' | ||
*'''[[Effect::Difficulty urinating]]'''- This effect is commonly reported by users. | *'''[[Effect::Difficulty urinating]]''' - This effect is commonly reported by users. | ||
*'''[[Effect::Frequent urination]]''' | *'''[[Effect::Frequent urination]]''' | ||
*'''[[Effect::Motor control loss]]''' | *'''[[Effect::Motor control loss]]''' - At higher doses this effect resembles that of [[benzodiazepines]] and [[alcohol]]. Users report stumbling and bumping in to walls. | ||
*'''[[Effect::Seizure suppression]]'''<ref>{{Citation | title=Pregabalin | url=https://www.epilepsy.com/tools-resources/seizure-medication-list/pregabalin}}</ref><ref>{{cite journal | vauthors=((Ryvlin, P.)), ((Perucca, E.)), ((Rheims, S.)) | journal=Neuropsychiatric Disease and Treatment | title=Pregabalin for the management of partial epilepsy | volume=4 | issue=6 | pages=1211–1224 | date= December 2008 | url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646650/ | issn=1176-6328}}</ref> | *'''[[Tactile suppression]]''' - This effect can result in the whole body feeling numb, particularly one’s face. At the same time the user’s sense of touch can be enhanced. | ||
*'''[[Effect::Seizure suppression]]''' - Pregabalin is effective at reducing certain types of seizures such as focal seizures and partial seizures.<ref>{{Citation | title=Pregabalin | url=https://www.epilepsy.com/tools-resources/seizure-medication-list/pregabalin}}</ref><ref>{{cite journal | vauthors=((Ryvlin, P.)), ((Perucca, E.)), ((Rheims, S.)) | journal=Neuropsychiatric Disease and Treatment | title=Pregabalin for the management of partial epilepsy | volume=4 | issue=6 | pages=1211–1224 | date= December 2008 | url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646650/ | issn=1176-6328}}</ref> | |||
}} | }} | ||