Antipsychotic: Difference between revisions
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'''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref> | '''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>{{cite book | vauthors=((Finkel, R.)), ((Clark, M. A.)), ((Cubeddu, L. X.)) | date= 2009 | title=Pharmacology | publisher=Lippincott Williams & Wilkins | isbn=9780781771559}}</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[Delusions|delusions]], [[External hallucinations|hallucinations]], or [[thought disorganization|disordered thought]]), particularly in [[wikipedia:schizophrenia|schizophrenia]] and [[wikipedia:bipolar disorder|bipolar disorder]]. | ||
First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, called atypical antipsychotics, have been developed more recently. The first atypical antipsychotic, [[clozapine]], was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's [[dopamine]] pathways; atypicals tend to act on [[serotonin]] receptors as well. | First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, called atypical antipsychotics, have been developed more recently. The first atypical antipsychotic, [[clozapine]], was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's [[dopamine]] pathways; atypicals tend to act on [[serotonin]] receptors as well. |