This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Deschloroketamine: Difference between revisions
>I0nny m Added legality for austria |
>Graham m wiki ref formatting |
||
| Line 3: | Line 3: | ||
{{SubstanceBox/Deschloroketamine}} | {{SubstanceBox/Deschloroketamine}} | ||
'''2'-Oxo-PCM''' (also known as '''deschloroketamine''', '''O-PCM''', '''DXE''', and '''DCK''') is a lesser-known novel [[psychoactive class::dissociative]] substance of the [[chemical class::arylcyclohexylamine]] class that produces [[dissociative]], [[pain relief|anesthetic]] and [[hallucinogenic]] effects when [[Routes of administration|administered]].<ref name="name">Synthesis and in vitro evaluation of (18)F-labelled S-fluoroalkyl diarylguanidines: Novel high-affinity NMDA receptor antagonists for imaging with PET | '''2'-Oxo-PCM''' (also known as '''deschloroketamine''', '''O-PCM''', '''DXE''', and '''DCK''') is a lesser-known novel [[psychoactive class::dissociative]] substance of the [[chemical class::arylcyclohexylamine]] class that produces [[dissociative]], [[pain relief|anesthetic]] and [[hallucinogenic]] effects when [[Routes of administration|administered]].<ref name="name">{{cite journal | vauthors=((Robins, E. G.)), ((Zhao, Y.)), ((Khan, I.)), ((Wilson, A.)), ((Luthra, S. K.)), ((Rstad, E.)) | journal=Bioorganic & Medicinal Chemistry Letters | title=Synthesis and in vitro evaluation of (18)F-labelled S-fluoroalkyl diarylguanidines: Novel high-affinity NMDA receptor antagonists for imaging with PET | volume=20 | issue=5 | pages=1749–1751 | date=1 March 2010 | issn=1464-3405 | doi=10.1016/j.bmcl.2010.01.052}}</ref><ref name="patent">{{Citation | vauthors=((Stevens, C. L.)) | title=Aminoketones and methods for their production | url=https://patents.google.com/patent/US3254124/en}}</ref> | ||
Early discussion over DCK has revolved around speculation over claims of antibacterial or immunosuppressant properties. If this speculation is valid, it is possible that its prolonged use could potentially pose a serious threat to one's health and immune system, which is why misuse of this substance is highly discouraged.<ref name="DCKAntibacterial">Preiss, D., | Early discussion over DCK has revolved around speculation over claims of antibacterial or immunosuppressant properties. If this speculation is valid, it is possible that its prolonged use could potentially pose a serious threat to one's health and immune system, which is why misuse of this substance is highly discouraged.<ref name="DCKAntibacterial">{{Citation | vauthors=((Preiss, D.)), ((Tatar, A.)) | title=Use of 2-methylamino-2-phenylcyclohexanone for the treatment of bacterial, fungal, virus or protozoan infections as well as for immunomodulation | url=https://patents.google.com/patent/US5811464/en}}</ref> Ketamine has been found to have similar properties.<ref>{{cite journal | vauthors=((Gocmen, S.)), ((Buyukkocak, U.)), ((Caglayan, O.)) | journal=Upsala Journal of Medical Sciences | title=In vitro investigation of the antibacterial effect of ketamine | volume=113 | issue=1 | pages=39–46 | date= 2008 | issn=2000-1967 | doi=10.3109/2000-1967-211}}</ref> | ||
DCK has become easily accessible through online [[research chemical]] vendors<ref name="name" /> where it is being sold as a [[designer drug]].<ref>Characterization of the | DCK has become easily accessible through online [[research chemical]] vendors<ref name="name" /> where it is being sold as a [[designer drug]].<ref>{{cite journal | vauthors=((Frison, G.)), ((Zamengo, L.)), ((Zancanaro, F.)), ((Tisato, F.)), ((Traldi, P.)) | journal=Rapid communications in mass spectrometry: RCM | title=Characterization of the designer drug deschloroketamine (2-methylamino-2-phenylcyclohexanone) by gas chromatography/mass spectrometry, liquid chromatography/high-resolution mass spectrometry, multistage mass spectrometry, and nuclear magnetic resonance | volume=30 | issue=1 | pages=151–160 | date=15 January 2016 | issn=1097-0231 | doi=10.1002/rcm.7425}}</ref><ref>Alert: descloroketamina sold as ketamine in Barcelona | http://energycontrol.org/analisis-de-sustancias/resultados/alertas/560-alerta-descloroketamina-vendida-como-ketamina-en-barcelona.html</ref><ref>{{Citation | vauthors=((Villalba, J.)) | year=2015 | title=Los efectos desconocidos de la sequía de ketamina | url=https://www.vice.com/es/article/9b7yvp/los-efectos-desconocidos-de-la-sequia-de-ketamina-719}}</ref> <!-- DCK has been extinct multiple times but has returned and is still for sale. Users repor the quality has significantly degraded after around 2018 (will wword this better)--> | ||
Very little data exists about the pharmacological properties, metabolism, and toxicity of DCK, and it has a very brief history of human usage. It is strongly recommended that one use [[responsible drug use|harm reduction practices]] if choosing to use this substance. | Very little data exists about the pharmacological properties, metabolism, and toxicity of DCK, and it has a very brief history of human usage. It is strongly recommended that one use [[responsible drug use|harm reduction practices]] if choosing to use this substance. | ||
| Line 157: | Line 157: | ||
*'''Germany:''' Deschloroketamine is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]|access-date=December 10, 2019|language=de}}</ref> as of July 18, 2019.<ref>{{cite web|url=http://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl119s1083.pdf|title=Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes|publisher=Bundesanzeiger Verlag|work=Bundesgesetzblatt Jahrgang 2019 Teil I Nr. 27|pages=1083-1094|publication-date=July 17, 2019|access-date=January 1, 2020|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]|access-date=December 10, 2019|language=de}}</ref> | *'''Germany:''' Deschloroketamine is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]|access-date=December 10, 2019|language=de}}</ref> as of July 18, 2019.<ref>{{cite web|url=http://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl119s1083.pdf|title=Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes|publisher=Bundesanzeiger Verlag|work=Bundesgesetzblatt Jahrgang 2019 Teil I Nr. 27|pages=1083-1094|publication-date=July 17, 2019|access-date=January 1, 2020|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]|access-date=December 10, 2019|language=de}}</ref> | ||
*'''Switzerland:''' Deschloroketamine is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | *'''Switzerland:''' Deschloroketamine is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | ||
*'''United Kingdom:''' Deschloroketamine is a class B drug in the UK and is illegal to possess, produce, supply, or import. As an N-alkyl derivative of 2-Amino-2-phenylcyclohexanone, it is covered by the arylcyclohexylamine generic clause added to the Misuse of Drugs Act by S.I. 2013/239, which came into effect on the 26th February 2013.<ref>The Misuse of Drugs Act 1971 (Amendment) Order 2013 | *'''United Kingdom:''' Deschloroketamine is a class B drug in the UK and is illegal to possess, produce, supply, or import. As an N-alkyl derivative of 2-Amino-2-phenylcyclohexanone, it is covered by the arylcyclohexylamine generic clause added to the Misuse of Drugs Act by S.I. 2013/239, which came into effect on the 26th February 2013.<ref>{{Citation | title=The Misuse of Drugs Act 1971 (Amendment) Order 2013 | url=https://www.legislation.gov.uk/uksi/2013/239/introduction/made}}</ref> | ||
*'''Czech Republic:''' Deschloroketamine is illegal in the Czech Republic.<ref>https://www.zakonyprolidi.cz/cs/2013-463</ref> | *'''Czech Republic:''' Deschloroketamine is illegal in the Czech Republic.<ref>{{Citation | vauthors=(([email protected], A. C.-)) | title=463/2013 Sb. Nařízení vlády o seznamech návykových látek | url=https://www.zakonyprolidi.cz/cs/2013-463}}</ref> | ||
*'''Austria:''' Deschloroketamine is illegal in Austria under the NPSV (Neue-Psychoaktive-Substanzen-Verordnung).<ref>https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=20007642</ref> | *'''Austria:''' Deschloroketamine is illegal in Austria under the NPSV (Neue-Psychoaktive-Substanzen-Verordnung).<ref>{{Citation | title=RIS - Neue-Psychoaktive-Substanzen-Verordnung - Bundesrecht konsolidiert, Fassung vom 21.07.2022 | url=https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=20007642}}</ref> | ||
==See also== | ==See also== | ||