25B-NBOMe: Difference between revisions
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25B-NBOMe is a relatively new substance, and little is known about its pharmacological risks or its interaction with other substances. The lethal dosage has not yet been determined. One case has been reported on where 25B-NBOMe was identified as the cause of death for a 17-year-old boy.<ref>{{Citation | title=Designer Drug Identified As Cause Of Plano Teen’s Death | url=https://www.cbsnews.com/dfw/news/designer-drug-identified-as-cause-of-plano-teens-death/}}</ref> | 25B-NBOMe is a relatively new substance, and little is known about its pharmacological risks or its interaction with other substances. The lethal dosage has not yet been determined. One case has been reported on where 25B-NBOMe was identified as the cause of death for a 17-year-old boy.<ref>{{Citation | title=Designer Drug Identified As Cause Of Plano Teen’s Death | url=https://www.cbsnews.com/dfw/news/designer-drug-identified-as-cause-of-plano-teens-death/}}</ref> | ||
It is advised that due to 25B-NBOMe's extreme potency it should not be insufflated as this method of administration is [[Toxicity::potentially fatal at heavy dosages]].<ref name=" | It is advised that due to 25B-NBOMe's extreme potency it should not be insufflated as this method of administration is [[Toxicity::potentially fatal at heavy dosages]].<ref name="25Xfatal">{{Citation | title=Erowid NBOMe (Other or Unknown NBOMe-Compound) Vault : Fatalities / Deaths | url=https://www.erowid.org/chemicals/nbome/nbome_death.shtml}}</ref> | ||
25B-NBOMe has been used in clinical trials with an evaluation dose for safety consideration to humans of only 1 microgram; Such a dose is 300× lower than the dose expected to be hallucinogenic to humans and it is expected that recreational use would greatly exceed doses determined to be safe to humans.<ref>Preclinical Safety Assessment of the 5-HT2A | 25B-NBOMe has been used in clinical trials with an evaluation dose for safety consideration to humans of only 1 microgram; Such a dose is 300× lower than the dose expected to be hallucinogenic to humans and it is expected that recreational use would greatly exceed doses determined to be safe to humans.<ref>Preclinical Safety Assessment of the 5-HT2A |