Methylphenidate: Difference between revisions
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'''Methylphenidate''' (also known as '''MPH''', '''MPD''', and the trade names '''Ritalin''', '''Concerta''', and '''Methylin''', among others) is a | '''Methylphenidate''' (also known as '''MPH''', '''MPD''', and the trade names '''Ritalin''', '''Concerta''', and '''Methylin''', among others) is a classical [[psychoactive class::stimulant]] substance of the [[chemical class::phenidate]] class. It is the parent compound of the [[substituted phenidates]], a family of stimulants that includes [[ethylphenidate]], [[isopropylphenidate]], and others. The mechanism of action involves reuptake inhibition of the [[neurotransmitters]] [[dopamine]] and [[norepinephrine]]. | ||
It was first synthesized in 1944 and was approved for medical use in the United States in 1955. It was originally sold by Swiss company CIBA (now Novartis).<ref>Lange KW, Reichl S, Lange KM, Tucha L, Tucha O (December 2010). "The history of attention deficit hyperactivity disorder". Attention Deficit and Hyperactivity Disorders. 2 (4): 241–255. doi:10.1007/s12402-010-0045-8. PMC 3000907. PMID 21258430.</ref> It is approved for treatment of attention-deficit hyperactivity disorder (ADHD) and narcolepsy. It is often used by students with or without ADHD to enhance their mental abilities, improve their concentration, and help them study. | It was first synthesized in 1944 and was approved for medical use in the United States in 1955. It was originally sold by Swiss company CIBA (now Novartis).<ref>Lange KW, Reichl S, Lange KM, Tucha L, Tucha O (December 2010). "The history of attention deficit hyperactivity disorder". Attention Deficit and Hyperactivity Disorders. 2 (4): 241–255. doi:10.1007/s12402-010-0045-8. PMC 3000907. PMID 21258430.</ref> It is approved for treatment of attention-deficit hyperactivity disorder (ADHD) and narcolepsy. It is often used by students with or without ADHD to enhance their mental abilities, improve their concentration, and help them study. |