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Pregabalin: Difference between revisions
>Mandudebro902102 volumetric elimination not supported by the cited source. |
>Mandudebro902102 Added half life |
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Pregabalin undergoes negligible metabolism in humans. In experiments using nuclear medicine techniques, it was revealed that approximately 98% of the radioactivity recovered in the urine was unchanged pregabalin. The primary metabolite is N-methyl pregabalin. | Pregabalin undergoes negligible metabolism in humans. In experiments using nuclear medicine techniques, it was revealed that approximately 98% of the radioactivity recovered in the urine was unchanged pregabalin. The primary metabolite is N-methyl pregabalin. | ||
Pregabalin is eliminated from the systemic circulation primarily by renal excretion as unchanged substance.<ref>http://web.archive.org/web/20160305071130/http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=41099</ref> | Pregabalin is eliminated from the systemic circulation primarily by renal excretion as unchanged substance.<ref>http://web.archive.org/web/20160305071130/http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=41099</ref> The elimination half life is 6.3 hours.<ref>https://go.drugbank.com/drugs/DB00230</ref> | ||
==Subjective effects== | ==Subjective effects== | ||