Adrenaline: Difference between revisions
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'''Adrenaline''' (also known as '''epinephrine''') is a [[hormone]] and [[neurotransmitter]]. It is primarily produced in the adrenal glands and certain neurons in humans and animals.{{clarify}}{{citation needed}} | '''Adrenaline''' (also known as '''epinephrine''') is a [[hormone]] and [[neurotransmitter]]. It is primarily produced in the adrenal glands and certain neurons in humans and animals.{{clarify}}{{citation needed}} | ||
Adrenaline is used to regulate heart rate, blood vessel and air passage diameters, and metabolic shifts. Adrenaline release is a crucial component of the fight-or-flight response of the sympathetic nervous system.{{citation needed}} | Adrenaline is used to regulate heart rate, blood vessel and air passage diameters, and metabolic shifts. Adrenaline release is a crucial component of the fight-or-flight response of the sympathetic nervous system.{{citation needed}} Adrenaline release during fight-or-flight can increase the rate of processing of information in the brain which leads to a slow motion perception due to the relativity of intertwined space and time as [https://en.wikipedia.org/wiki/Spacetime spacetime]. | ||
==Chemistry== | ==Chemistry== | ||
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===Drugs targeting the adrenergic system=== | ===Drugs targeting the adrenergic system=== | ||
*'''Direct-acting agonists''' | *'''Direct-acting agonists''' | ||
Direct-acting [[agonists]] have direct action upon the adrenergic system where they have action upon the adrenergic receptors themselves. These include antihypertensives (to reduce blood pressure), [[sedatives]] and [[muscle relaxants]]. | Direct-acting [[agonists]] have direct action upon the adrenergic system where they have action upon the adrenergic receptors themselves. These include antihypertensives (to reduce blood pressure), [[sedatives]] and [[muscle relaxants]]. | ||
*'''Indirect-acting agonists''' | *'''Indirect-acting agonists''' | ||
Indirect [[agonists]] work by increasing the [[neurotransmission]] of endogenous chemicals such as adrenaline or [[noradrenaline]]. These include many [[stimulant]] drugs, such as [[amphetamine]], [[cocaine]], [[MDMA]] and [[methylphenidate]]. | Indirect [[agonists]] work by increasing the [[neurotransmission]] of endogenous chemicals such as adrenaline or [[noradrenaline]]. These include many [[stimulant]] drugs, such as [[amphetamine]], [[cocaine]], [[MDMA]] and [[methylphenidate]]. | ||
*'''Antagonists''' | *'''Antagonists''' | ||
[[Antagonists]] of the adrenergic system can be split into α-blockers and β-blockers. These include [[antipsychotics]], [[antidepressants]] and in medication preventing heart attacks. | [[Antagonists]] of the adrenergic system can be split into α-blockers and β-blockers. These include [[antipsychotics]], [[antidepressants]] and in medication preventing heart attacks. | ||
==See also== | ==See also== | ||
*[[Responsible use]] | *[[Responsible use]] | ||
*[[Acetylcholine]] | *[[Acetylcholine]] | ||
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==External links== | ==External links== | ||
*[https://en.wikipedia.org/wiki/Adrenaline Adrenaline (Wikipedia)] | *[https://en.wikipedia.org/wiki/Adrenaline Adrenaline (Wikipedia)] | ||