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Serotonin: Difference between revisions
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Serotonin is comprised of a monoamine chain attached to an indole ring at the third carbon. A monoamine chain is made up of an amine group attached to an ethane chain. | Serotonin is comprised of a monoamine chain attached to an indole ring at the third carbon. A monoamine chain is made up of an amine group attached to an ethane chain. | ||
This monoamine chain can be found in many neurotransmitters, including [[histamine|histamine]], [[dopamine|dopamine]], [[adrenaline|adrenaline]] and [[noradrenaline|noradrenaline]]. It is also found in many drugs, | This monoamine chain can be found in many neurotransmitters, including [[histamine|histamine]], [[dopamine|dopamine]], [[adrenaline|adrenaline]] and [[noradrenaline|noradrenaline]]. It is also found in many drugs, e.g. [[tryptamines]] and [[phenethylamines]]. | ||
Serotonin is synthesized from the α-amino acid tryptophan, which is hydroxylated into the metabolic intermediate [[5-Hydroxytryptophan]] (5-HTP) and then decarboxylated into serotonin. This process requires the co-enzyme vitamin B6.{{citation needed}} | Serotonin is synthesized from the α-amino acid tryptophan, which is hydroxylated into the metabolic intermediate [[5-Hydroxytryptophan]] (5-HTP) and then decarboxylated into serotonin. This process requires the co-enzyme vitamin B6.{{citation needed}} | ||