Serotonin: Difference between revisions
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[[File:Indole_numbered.png|210px|thumb|right|Skeletal formula of indole molecule with ring positions numbered.]] | [[File:Indole_numbered.png|210px|thumb|right|Skeletal formula of indole molecule with ring positions numbered.]] | ||
[[File:Monoamine_chain.png|210px|thumb|right|Skeletal formula of monoamine chain molecule.]] | [[File:Monoamine_chain.png|210px|thumb|right|Skeletal formula of monoamine chain molecule.]] | ||
Serotonin is comprised of a monoamine chain attached to an indole ring at the third carbon. A monoamine chain is made up of an amine group attached to an ethane chain. This monoamine chain can be found in many neurotransmitters, including [[histamine|histamine]], [[dopamine|dopamine]], [[adrenaline|adrenaline]] and [[noradrenaline|noradrenaline]]. It is also found in many drugs, examples being [[tryptamines]] and [[phenethylamines]]. | Serotonin is comprised of a monoamine chain attached to an indole ring at the third carbon. A monoamine chain is made up of an amine group attached to an ethane chain. | ||
This monoamine chain can be found in many neurotransmitters, including [[histamine|histamine]], [[dopamine|dopamine]], [[adrenaline|adrenaline]] and [[noradrenaline|noradrenaline]]. It is also found in many drugs, examples being [[tryptamines]] and [[phenethylamines]]. | |||
Serotonin is synthesized from the α-amino acid tryptophan. Tryptophan is hydroxylated into the metabolic intermediate [[5-Hydroxytryptophan]] (5-HTP) and then decarboxylated into serotonin. This process requires the co-enzyme vitamin B6.{{citation needed}} | Serotonin is synthesized from the α-amino acid tryptophan. Tryptophan is hydroxylated into the metabolic intermediate [[5-Hydroxytryptophan]] (5-HTP) and then decarboxylated into serotonin. This process requires the co-enzyme vitamin B6.{{citation needed}} |