Serotonergic psychedelic: Difference between revisions

Line 18:

The disruption of the neurotransmitter balance causes these control loops to collapse overwhelmed, leading to the flooding of the frontal lobe with neuronal excitatory glutamate; internal and external stimuli as well as all kinds of non-conscious contents can freely move up to the cerebral cortex and appear as visions in consciousness.<ref>Vollenweider, F. X. (2001). Brain mechanisms of hallucinogens and entactogens. Dialogues in Clinical Neuroscience, 3(4), 265–79. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3181663&tool=pmcentrez&rendertype=abstract</ref><ref>[http://www.neuroculturelab.com/portfolio/edelrausch-im-labor/ Edelrausch im Labor] – ''Neuro Culture Lab'' (German)</ref>

Furthermore, ~~there is an~~ over-activation of the locus ~~coerlueus~~ and ~~thereby~~ widespread [[norepinephrine]] secretion, causing a state of ~~spiritual~~ transcendence and sometimes even intense spiritual experiences.

Furthermore, over-activation of the ''locus coeruleus'' and subsequent widespread [[norepinephrine]] secretion may occur, causing a perceived state of sensory transcendence and sometimes even intense spiritual or [[transpersonal]] experiences.

It is worth noting that [[selective serotonin reuptake inhibitors]] (a class of [[antidepressants]] including Paxil, Prozac, and Zoloft) can increase the dosage required for hallucinogenic effects in some people (based on anecdotal reports). Some users, however, have found this to be entirely untrue for them, so those who are using daily antidepressants should, at first, only attempt a common dosage.

@@ Line 18: / Line 18: @@
 The disruption of the neurotransmitter balance causes these control loops to collapse overwhelmed, leading to the flooding of the frontal lobe with neuronal excitatory glutamate; internal and external stimuli as well as all kinds of non-conscious contents can freely move up to the cerebral cortex and appear as visions in consciousness.<ref>Vollenweider, F. X. (2001). Brain mechanisms of hallucinogens and entactogens. Dialogues in Clinical Neuroscience, 3(4), 265–79. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3181663&tool=pmcentrez&rendertype=abstract</ref><ref>[http://www.neuroculturelab.com/portfolio/edelrausch-im-labor/ Edelrausch im Labor] – ''Neuro Culture Lab'' (German)</ref>
-Furthermore, there is an over-activation of the locus coerlueus and thereby widespread [[norepinephrine]] secretion, causing a state of spiritual transcendence and sometimes even intense spiritual experiences.
+Furthermore, over-activation of the ''locus coeruleus'' and subsequent widespread [[norepinephrine]] secretion may occur, causing a perceived state of sensory transcendence and sometimes even intense spiritual or [[transpersonal]] experiences.
 It is worth noting that [[selective serotonin reuptake inhibitors]] (a class of [[antidepressants]] including Paxil, Prozac, and Zoloft) can increase the dosage required for hallucinogenic effects in some people (based on anecdotal reports). Some users, however, have found this to be entirely untrue for them, so those who are using daily antidepressants should, at first, only attempt a common dosage.