A-PHP: Difference between revisions
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'''alpha-Pyrrolidinohexiophenone''' (also known as '''PV-7''', '''alpha-PHP''', '''A-PHP''', and '''α-PHP''') is a lesser-known novel [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] class. It is structurally related to | '''alpha-Pyrrolidinohexiophenone''' (also known as '''PV-7''', '''alpha-PHP''', '''A-PHP''', and '''α-PHP''') is a lesser-known novel [[psychoactive class::stimulant]] substance of the [[chemical class::cathinone]] class. It is structurally related to [[MDPV]] and is one of the successors to the [[designer drug]] [[Substituted cathinone|cathinone]] analog [[A-PVP|α-PVP]]. | ||
It is being used and marketed as a replacement for [[α-PVP]] (known on the street as ''flakka'') a few years following its ban, where it has come to substitute α-PVP in many parts of the world. While initially mass synthesized in Chinese industrial laboratories, a ban on α-PHP within China's borders has forced production to nations worldwide.{{citation needed}} | |||
[[Subjective effects]] such as [[euphoria]], [[thought acceleration]], [[disinhibition]] and [[ego inflation]] when [[Routes of administration|administered]]. | [[Subjective effects]] such as [[euphoria]], [[thought acceleration]], [[disinhibition]] and [[ego inflation]] when [[Routes of administration|administered]]. It generally comes in the form of either a fine powder or crystallized shards that can produce powerful but short-lived euphoric stimulant effects comparable to those of vaporized [[methamphetamine]] and [[cocaine]]. Like its cathinone predecessors, it is has gained notoriety for its tendency to induce [[compulsive redosing]] and addictive behaviors as well the ability to produce [[Delusions|delusional states]] and [[psychosis]] when abused.{{citation needed}} | ||
α-PHP | Very little data exists about the pharmacological properties, metabolism, and toxicity of α-PHP. It has recently become commonly marketed alongside [[research chemical]] [[stimulants]] like [[NEP]] and [[Hexen]] as a legal, grey-market alternative to [[a-PVP]], and commercially distributed through online [[research chemical]] vendors. | ||
It is highly advised to use [[harm reduction practices]] if using this substance. | |||
==Chemistry== | ==Chemistry== | ||
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*'''United States''': α-PHP in the past has been assigned to Schedule I on a Temporary Placement basis, although the order has expired without renewal or permanent placement and is no longer Scheduled at the Federal level as of July 2021.<ref>{{cite web | title = Schedules of Controlled Substances: Temporary Placement of N-Ethylhexedrone, α-PHP, 4-MEAP, MPHP, PV8, and 4-Chloro-α-PVP in Schedule I | url = https://www.deadiversion.usdoj.gov/fed_regs/rules/2019/fr0501.htm | publisher = Drug Enforcement Administration | access-date = 2021-05-31 | archive-date = 2021-04-30 | archive-url = https://web.archive.org/web/20210430020931/https://www.deadiversion.usdoj.gov/fed_regs/rules/2019/fr0501.htm | url-status = live }}</ref> Despite this however, α-PHP may be considered an analogue of α-PVP, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.<ref>https://www.law.cornell.edu/uscode/text/21/813</ref> | *'''United States''': α-PHP in the past has been assigned to Schedule I on a Temporary Placement basis, although the order has expired without renewal or permanent placement and is no longer Scheduled at the Federal level as of July 2021.<ref>{{cite web | title = Schedules of Controlled Substances: Temporary Placement of N-Ethylhexedrone, α-PHP, 4-MEAP, MPHP, PV8, and 4-Chloro-α-PVP in Schedule I | url = https://www.deadiversion.usdoj.gov/fed_regs/rules/2019/fr0501.htm | publisher = Drug Enforcement Administration | access-date = 2021-05-31 | archive-date = 2021-04-30 | archive-url = https://web.archive.org/web/20210430020931/https://www.deadiversion.usdoj.gov/fed_regs/rules/2019/fr0501.htm | url-status = live }}</ref> Despite this however, α-PHP may be considered an analogue of α-PVP, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.<ref>https://www.law.cornell.edu/uscode/text/21/813</ref> | ||
==See also== | |||
*[[Responsible use]] | *[[Responsible use]] | ||
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*[[MDPV]] | *[[MDPV]] | ||
*[[α-PVP]] | *[[α-PVP]] | ||
==External links== | ==External links== |