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Although many psychoactive substances are reasonably safe to use on their own, they can suddenly become dangerous or even life-threatening when combined with other substances. The following list includes some known dangerous combinations (although it is not guaranteed to include all of them). | ''Although many psychoactive substances are reasonably safe to use on their own, they can suddenly become dangerous or even life-threatening when combined with other substances. The following list includes some known dangerous combinations (although it is not guaranteed to include all of them). | ||
Independent research (e.g. [https://www.google.com Google], [https://www.duckduckgo.com DuckDuckGo]) should ''always'' be conducted to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from [https://combo.tripsit.me TripSit]. | Independent research (e.g. [https://www.google.com Google], [https://www.duckduckgo.com DuckDuckGo]) should ''always'' be conducted to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from [https://combo.tripsit.me TripSit].'' | ||