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Gabapentin: Difference between revisions
>Gabagaba This line references a study on "gabapentin enacarbil", which is not the same as gabapentin. |
>Utaninja Added another study that tested the theory of the previously mentioned FDA study on suicide risk for gabapentin and also added a note from that study that showed that the studies are most likely inaccurate to a degree. |
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===Suicide=== | ===Suicide=== | ||
In 2009, the U.S. Food and Drug Administration issued a warning of an increased risk of depression and suicidal thoughts and behaviors in patients taking gabapentin (along with other [[anticonvulsant]] drugs),<ref>http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm100190.htm</ref> modifying the packaging insert to reflect this. A 2010 meta-analysis confirmed the increased risk of suicide associated with gabapentin use.<ref>https://www.ncbi.nlm.nih.gov/pubmed/20388896</ref> | In 2009, the U.S. Food and Drug Administration issued a warning of an increased risk of depression and suicidal thoughts and behaviors in patients taking gabapentin (along with other [[anticonvulsant]] drugs),<ref>http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm100190.htm</ref> modifying the packaging insert to reflect this. A 2010 meta-analysis confirmed the increased risk of suicide associated with gabapentin use.<ref>https://www.ncbi.nlm.nih.gov/pubmed/20388896</ref> | ||
In 2010, a study conducted by Patorno E, Bohn RL, Wahl PM, et al, found that the use of gabapentin compared to the use of [[topiramate]] may be associated with an increase in suicidal acts and or violent deaths.<ref>https://jamanetwork.com/journals/jama/fullarticle/185674</ref> | |||
It should be noted that in both studies along with others that the patients evaluated had a higher suicide risk and the studies were both limited and imprecise.<ref>https://www.ncbi.nlm.nih.gov/pubmed/20388896</ref> | |||
===Lethal dosage=== | ===Lethal dosage=== | ||