HXE: Difference between revisions

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HXE's effects resemble rather the effects of [[MXPr]], [[MXE]], [[DCK]] than more chaotic derivatives like [[O-PCE]] or [[MXiPr]]. Compared to [[MXE]], it has less of a warmth to it and is weaker in its euphoria and clearheadedness.

HXE's effects resemble rather the effects of [[MXPr]], [[MXE]], [[DCK]] than more chaotic derivatives like [[O-PCE]] or [[MXiPr]]. Compared to [[MXE]], it has less of a warmth to it and is weaker in its euphoria and clearheadedness, which can roughly be considered equal to [MXPr]]'s potency.

{{effects/base

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|{{effects/cognitive|

~~If applicable~~, ~~a brief paragraph summary of the substance~~'s cognitive effects ~~may~~ be ~~included here.~~

HXE is generally considered to be euphoric and comfortable. It can also turn mildly confusing, although it's manageable and not nearly as wild as [[O-PCE]] or [[MXiPr]]. It is mostly clear-headed in comparison to that of [[DXM]] and [[ketamine]]. The specific cognitive effects can be broken down into several separate subcomponents which are listed and described below:

~~You~~ may ~~select from a list~~ of ~~cognitive effects to add below~~ [[~~Subjective effect index#Cognitive effects|here~~]].

*'''[[Effect::Amnesia]]'''

*'''[[Effect::Anxiety suppression]]'''

*'''[[Effect::~~Cognitive effect1~~]]'''

*'''[[Effect::Cognitive euphoria]]'''

*'''[[Effect::~~Cognitive effect2~~]]'''

*'''[[Effect::Compulsive redosing]]'''

*'''[[Effect::~~Cognitive effect3~~]]'''

*'''[[Effect::Conceptual thinking]]'''

*'''[[Effect::Creativity enhancement]]'''

*'''[[Effect::Decreased libido]]''' - This is not experienced in all environments, as [[Effect::increased libido]] may also be experienced especially at lower dosage ranges.

*'''[[Effect::Déjà vu]]'''

*'''[[Effect::Depersonalization]]

*'''[[Effect::Derealization]]

*'''[[Effect::Disinhibition]]'''

*'''[[Effect::Dream potentiation]]'''

*'''[[Effect::Ego death]]'''

*'''[[Effect::Immersion enhancement]]'''

*'''[[Effect::Increased music appreciation]]'''

*'''[[Effect::analysis suppression]]

*'''[[Effect::Introspection]]'''

*'''[[Effect::Mania]]''' - This can potentially occur with users who are compulsively and regularly consuming large amounts of this compound. This effect occurs less often on HXE than it does on more stimulating dissociatives such as [[3-MeO-PCP]] or [[2'-Oxo-PCE]].

*'''[[Effect::Memory suppression]]'''

*'''[[Effect::Personal meaning enhancement]]'''

*'''[[Effect::Thought deceleration]]'''

*'''[[Effect::Time distortion]]'''

}}

{{effects/auditory|

~~If applicable, a brief paragraph summary of the substance's auditory effects may be included here.~~

~~You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].~~

*'''[[Effect::Auditory effect1]]'''

*'''[[Effect::Auditory effect2]]'''

}}

~~{{effects/multisensory|~~

~~If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.~~

~~You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].~~

*'''[[Effect::~~Multisensory effect1~~]]'''

*'''[[Effect::Auditory distortion|Distortions]]'''

*'''[[Effect::~~Multisensory effect2~~]]'''

*'''[[Effect::Auditory hallucinations|Hallucinations]]'''

*'''[[Effect::Auditory suppression|Suppression]]'''

}}

{{effects/transpersonal|

~~If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.~~

*'''[[Effect::Existential self-realization]]'''

*'''[[Effect::Unity and interconnectedness]]'''

~~You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].~~

*'''[[Effect::~~Transpersonal effect1~~]]'''

*'''[[Effect::~~Transpersonal effect2~~]]'''

}}

===Experience reports===

There are currently {{#ask:[[Category:~~SUBSTANCE~~]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].

There are currently {{#ask:[[Category:HXE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].

{{#ask: [[Category:~~SUBSTANCE~~]][[Category:Experience]]|format=ul|Columns=1}}

{{#ask: [[Category:HXE]][[Category:Experience]]|format=ul|Columns=1}}

<!--

Additional experience reports can be found here:

* [https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml Erowid Experience Vaults: SUBSTANCE]

-->

==Toxicity and harm potential==

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It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.

===Lethal dosage===

The lethal dosage of HXE is not known. Based on it's effect it could probably be assumed, that it might carry roughly the same risk of death like similar compounnds like [[DMXE]] or [[MXPr]].

===Tolerance and addiction potential===

As with other nmda receptor antagonists, the chronic use of HXE can be considered [[addiction potential::moderately addictive with a high potential for abuse]] and is capable of producing psychological dependence among certain users.

when addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage.

tolerance to many of the effects of HXE [[time to full tolerance::develops with prolonged and repeated use]].

this results in users having to administer increasingly large doses to achieve the same effects.

after that, it takes about [[time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption).

HXE presents cross-tolerance with [[cross-tolerance::all [[dissociative]]s]], meaning that after the consumption of mxe all [[dissociative]]s will have a reduced effect.

===Dangerous interactions===

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==Legal status==

*'''Switzerland:''' HXE can be considered a specially defined derivative of PCE or O-PCE and is therefore illegal.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>

*'''United Kingdom''': HXE is illegal in the United Kingdom.{{citation needed}}

*'''United States''': HXE is not illegal, however, if it is sold with the intention for human consumption (such as in capsules) it becomes illegal to possess under the Federal Analogue Act. This is avoided by placing the label "not for human consumption" on the container of the chemical.{{citation needed}}

==See also==

*[[Responsible use]]

*[[MXE]]

*[[MXPr]]

*[[Dissociative]]

==External links==

* https://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=7505&name=HXE

~~==Literature==~~

* APA formatted reference

~~Please see the [[citation formatting guide]] if you need assistance properly formatting citations.~~

==References==

@@ Line 246: / Line 246: @@
 {{Preamble/SubjectiveEffects}}
-HXE's effects resemble rather the effects of [[MXPr]], [[MXE]], [[DCK]] than more chaotic derivatives like [[O-PCE]] or [[MXiPr]]. Compared to [[MXE]], it has less of a warmth to it and is weaker in its euphoria and clearheadedness.
+HXE's effects resemble rather the effects of [[MXPr]], [[MXE]], [[DCK]] than more chaotic derivatives like [[O-PCE]] or [[MXiPr]]. Compared to [[MXE]], it has less of a warmth to it and is weaker in its euphoria and clearheadedness, which can roughly be considered equal to [MXPr]]'s potency.
 {{effects/base
@@ Line 302: / Line 302: @@
 |{{effects/cognitive|
-If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
+HXE is generally considered to be euphoric and comfortable. It can also turn mildly confusing, although it's manageable and not nearly as wild as [[O-PCE]] or [[MXiPr]]. It is mostly clear-headed in comparison to that of [[DXM]] and [[ketamine]]. The specific cognitive effects can be broken down into several separate subcomponents which are listed and described below:
-You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
+*'''[[Effect::Amnesia]]'''
+*'''[[Effect::Anxiety suppression]]'''
-*'''[[Effect::Cognitive effect1]]'''
+*'''[[Effect::Cognitive euphoria]]'''
-*'''[[Effect::Cognitive effect2]]'''
+*'''[[Effect::Compulsive redosing]]'''
-*'''[[Effect::Cognitive effect3]]'''
+*'''[[Effect::Conceptual thinking]]'''
+*'''[[Effect::Creativity enhancement]]'''
+*'''[[Effect::Decreased libido]]''' - This is not experienced in all environments, as [[Effect::increased libido]] may also be experienced especially at lower dosage ranges.
+*'''[[Effect::Déjà vu]]'''
+*'''[[Effect::Depersonalization]]
+*'''[[Effect::Derealization]]
+*'''[[Effect::Disinhibition]]'''
+*'''[[Effect::Dream potentiation]]'''
+*'''[[Effect::Ego death]]'''
+*'''[[Effect::Immersion enhancement]]'''
+*'''[[Effect::Increased music appreciation]]'''
+*'''[[Effect::analysis suppression]]
+*'''[[Effect::Introspection]]'''
+*'''[[Effect::Mania]]''' - This can potentially occur with users who are compulsively and regularly consuming large amounts of this compound. This effect occurs less often on HXE than it does on more stimulating dissociatives such as [[3-MeO-PCP]] or [[2'-Oxo-PCE]].
+*'''[[Effect::Memory suppression]]'''
+*'''[[Effect::Personal meaning enhancement]]'''
+*'''[[Effect::Thought deceleration]]'''
+*'''[[Effect::Time distortion]]'''
 }}
 {{effects/auditory|
-If applicable, a brief paragraph summary of the substance's auditory effects may be included here.
-You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].
-*'''[[Effect::Auditory effect1]]'''
-*'''[[Effect::Auditory effect2]]'''
-}}
-{{effects/multisensory|
-If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.
-You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].
-*'''[[Effect::Multisensory effect1]]'''
+*'''[[Effect::Auditory distortion|Distortions]]'''
-*'''[[Effect::Multisensory effect2]]'''
+*'''[[Effect::Auditory hallucinations|Hallucinations]]'''
+*'''[[Effect::Auditory suppression|Suppression]]'''
 }}
 {{effects/transpersonal|
-If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.
+*'''[[Effect::Existential self-realization]]'''
+*'''[[Effect::Unity and interconnectedness]]'''
-You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].
-*'''[[Effect::Transpersonal effect1]]'''
-*'''[[Effect::Transpersonal effect2]]'''
 }}
 }}
 ===Experience reports===
-There are currently {{#ask:[[Category:SUBSTANCE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].
+There are currently {{#ask:[[Category:HXE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].
-{{#ask: [[Category:SUBSTANCE]][[Category:Experience]]|format=ul|Columns=1}}
+{{#ask: [[Category:HXE]][[Category:Experience]]|format=ul|Columns=1}}
+<!--
 Additional experience reports can be found here:
 * [https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml Erowid Experience Vaults: SUBSTANCE] <!-- Check the link to see if it exists -->
+-->
 ==Toxicity and harm potential==
 {{toxicity}}
@@ Line 351: / Line 354: @@
 It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
 ===Lethal dosage===
+The lethal dosage of HXE is not known. Based on it's effect it could probably be assumed, that it might carry roughly the same risk of death like similar compounnds like [[DMXE]] or [[MXPr]].
 ===Tolerance and addiction potential===
+As with other nmda receptor antagonists, the chronic use of HXE can be considered [[addiction potential::moderately addictive with a high potential for abuse]] and is capable of producing psychological dependence among certain users.
+when addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage.
+tolerance to many of the effects of HXE [[time to full tolerance::develops with prolonged and repeated use]].
+this results in users having to administer increasingly large doses to achieve the same effects.
+after that, it takes about [[time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption).
+HXE presents cross-tolerance with [[cross-tolerance::all [[dissociative]]s]], meaning that after the consumption of mxe all [[dissociative]]s will have a reduced effect.
 ===Dangerous interactions===
 {{DangerousInteractions}}
@@ Line 359: / Line 374: @@
 ==Legal status==
 {{LegalStub}}
+*'''Switzerland:''' HXE can be considered a specially defined derivative of PCE or O-PCE and is therefore illegal.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>
+*'''United Kingdom''': HXE is illegal in the United Kingdom.{{citation needed}}
+*'''United States''': HXE is not illegal, however, if it is sold with the intention for human consumption (such as in capsules) it becomes illegal to possess under the Federal Analogue Act. This is avoided by placing the label "not for human consumption" on the container of the chemical.{{citation needed}}
 ==See also==
 *[[Responsible use]]
+*[[MXE]]
+*[[MXPr]]
+*[[Dissociative]]
 ==External links==
 {{#l:HXE.svg}}
 * https://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=7505&name=HXE
-==Literature==
-* APA formatted reference
-Please see the [[citation formatting guide]] if you need assistance properly formatting citations.
 ==References==