Brain zaps: Difference between revisions

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Brain zaps are most commonly induced under the influence of [[withdrawal]], dose reduction, and discontinuation of antidepressant drugs, including [[selective serotonin reuptake inhibitor|selective serotonin reuptake inhibitors]] (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) such as [[sertraline]], [[paroxetine]], and [[venlafaxine]]. [[Tramadol]], an [[opioid]] painkiller with SNRI properties, has also been reported to cause brain zaps upon abrupt discontinuation.<ref> "SSRIs and SNRIs: A review of the Discontinuation Syndrome in Children and Adolescents." (2011) by Hosenbocus S, MD FRCP(C) and Chahal R, MSW. | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024727/</ref><ref> "Fireworks or Brain Zaps? Antidepressants and brain zapping." (2011) By Jean Pollack, Ph.D. | https://www.psychologytoday.com/blog/creativity-way-life/201107/fireworks-or-brain-zaps</ref> If caused by antidepressant withdrawal, it is strongly recommended that one [[taper]] or reduce their dose gradually instead of stopping abruptly. This effect has been reported by anecdotal sources to occur in the days after a [[dosage#heavy|heavy]] [[dosage]] of [[MDMA]].<ref>Why You Get 'Brain Zaps' After Taking MDMA, and How You Can Stop Them (Vice) | https://www.vice.com/sv/article/bnkv45/brain-zaps-sleep-paralysis-mdma-ecstasy</ref>

~~Fish oil has~~ been reported to provide temporary relief from this affliction, although scientific literature supporting this claim is sparse.{{citation needed}}

Remedies to lessen the intensity or frequency of induced brain zaps include hydration (drinking enough water), supplementing for possible nutrient, vitamin or mineral deficiencies, getting adequate amounts of sleep, rest and stress relief.{{citation needed}}

Additionally, several compounds and nutrients have been reported to possibly provide temporary relief from this affliction, although scientific literature supporting this claim is sparse.{{citation needed}} The list includes:

* Magnesium

* Fish Oil (Omega 3)

* [[Melatonin]]

* [[5-HTP]] (5-HTP might paradoxically increase brain zaps, this substance should be taken with consideration)

* [[L-Tryptophan]]

* [[GABA]]

* [[Agmatine]]

* Spirulina

* B-Vitamin Complex, but without Vitamin B12

* [[Diphenhydramine]]

* [[Huperzine A]]

</onlyinclude>

===Psychoactive substances===

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 Brain zaps are most commonly induced under the influence of [[withdrawal]], dose reduction, and discontinuation of antidepressant drugs, including [[selective serotonin reuptake inhibitor|selective serotonin reuptake inhibitors]] (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) such as [[sertraline]], [[paroxetine]], and [[venlafaxine]]. [[Tramadol]], an [[opioid]] painkiller with SNRI properties, has also been reported to cause brain zaps upon abrupt discontinuation.<ref> "SSRIs and SNRIs: A review of the Discontinuation Syndrome in Children and Adolescents." (2011) by Hosenbocus S, MD FRCP(C) and Chahal R, MSW. | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024727/</ref><ref> "Fireworks or Brain Zaps? Antidepressants and brain zapping." (2011) By Jean Pollack, Ph.D. | https://www.psychologytoday.com/blog/creativity-way-life/201107/fireworks-or-brain-zaps</ref> If caused by antidepressant withdrawal, it is strongly recommended that one [[taper]] or reduce their dose gradually instead of stopping abruptly. This effect has been reported by anecdotal sources to occur in the days after a [[dosage#heavy|heavy]] [[dosage]] of [[MDMA]].<ref>Why You Get 'Brain Zaps' After Taking MDMA, and How You Can Stop Them (Vice) | https://www.vice.com/sv/article/bnkv45/brain-zaps-sleep-paralysis-mdma-ecstasy</ref>
-Fish oil has been reported to provide temporary relief from this affliction, although scientific literature supporting this claim is sparse.{{citation needed}}
+Remedies to lessen the intensity or frequency of induced brain zaps include hydration (drinking enough water), supplementing for possible nutrient, vitamin or mineral deficiencies, getting adequate amounts of sleep, rest and stress relief.{{citation needed}}
+Additionally, several compounds and nutrients have been reported to possibly provide temporary relief from this affliction, although scientific literature supporting this claim is sparse.{{citation needed}} The list includes:
+* Magnesium
+* Fish Oil (Omega 3)
+* [[Melatonin]]
+* [[5-HTP]] (5-HTP might paradoxically increase brain zaps, this substance should be taken with consideration)
+* [[L-Tryptophan]]
+* [[GABA]]
+* [[Agmatine]]
+* Spirulina
+* B-Vitamin Complex, but without Vitamin B12
+* [[Diphenhydramine]]
+* [[Huperzine A]]
 </onlyinclude>
 ===Psychoactive substances===