6-APB: Difference between revisions

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'''6-(2-Aminopropyl)benzofuran''' (also known as '''6-APB''' and '''"Benzofury"''') is a novel [[psychoactive class::entactogen]] substance of the [[chemical class::benzofuran]] class. It is structurally related to entactogens like [[MDA]], [[MDMA]], [[5-APB]], and [[5-MAPB]].

6-APB was first synthesized in 1993 by [[David E. Nichols]] as a potential non-neurotoxic alternative to [[MDMA]].<ref name="Nichols">Monte, A. P., Marona-Lewicka, D., Cozzi, N. V., & Nichols, D. E. (1993). Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3, 4-(methylenedioxy) amphetamine. Journal of Medicinal Chemistry, 36(23), ~~[[Tel:~~3700-3706|3700-3706]]. https://doi.org/10.1021/jm00075a027</ref> However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name "Benzofury" before its sale and import were subsequently banned.{{citation needed}}

6-APB was first synthesized in 1993 by [[David E. Nichols]] as a potential non-neurotoxic alternative to [[MDMA]].<ref name="Nichols">Monte, A. P., Marona-Lewicka, D., Cozzi, N. V., & Nichols, D. E. (1993). Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3, 4-(methylenedioxy) amphetamine. Journal of Medicinal Chemistry, 36(23), 3700-3706|3700-3706. https://doi.org/10.1021/jm00075a027</ref> However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name "Benzofury" before its sale and import were subsequently banned.{{citation needed}}

[[Subjective effects]] include [[anxiety suppression]], [[disinhibition]], [[muscle relaxation]], and [[euphoria]]. 6-APB's effects are commonly compared to those of [[MDA]] and other entactogens.

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==Reagent results==

Exposing compounds to the reagents gives a colour change which is indicative of the compound under test~~. The following test results are from [https://www.protestkit.eu/results/ protestkit]~~.

Exposing compounds to the reagents gives a colour change which is indicative of the compound under test.

{| class="wikitable"

!Compound

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|6-APB

|Purple

|Purple to black

|Purple - black

|Purple to black

|Purple - black

|Black

|Purple

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|6-APB succinate

|Purple

|Purple to black

|Purple - black

|Purple to black

|Purple - black

|Black

|Purple

@@ Line 3: / Line 3: @@
 '''6-(2-Aminopropyl)benzofuran''' (also known as '''6-APB''' and '''"Benzofury"''') is a novel [[psychoactive class::entactogen]] substance of the [[chemical class::benzofuran]] class. It is structurally related to entactogens like [[MDA]], [[MDMA]], [[5-APB]], and [[5-MAPB]].
--APB was first synthesized in 1993 by [[David E. Nichols]] as a potential non-neurotoxic alternative to [[MDMA]].<ref name="Nichols">Monte, A. P., Marona-Lewicka, D., Cozzi, N. V., & Nichols, D. E. (1993). Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3, 4-(methylenedioxy) amphetamine. Journal of Medicinal Chemistry, 36(23), [[Tel:3700-3706|3700-3706]]. https://doi.org/10.1021/jm00075a027</ref> However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name "Benzofury" before its sale and import were subsequently banned.{{citation needed}}
+-APB was first synthesized in 1993 by [[David E. Nichols]] as a potential non-neurotoxic alternative to [[MDMA]].<ref name="Nichols">Monte, A. P., Marona-Lewicka, D., Cozzi, N. V., & Nichols, D. E. (1993). Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3, 4-(methylenedioxy) amphetamine. Journal of Medicinal Chemistry, 36(23), 3700-3706|3700-3706. https://doi.org/10.1021/jm00075a027</ref> However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name "Benzofury" before its sale and import were subsequently banned.{{citation needed}}
 [[Subjective effects]] include [[anxiety suppression]], [[disinhibition]], [[muscle relaxation]], and [[euphoria]]. 6-APB's effects are commonly compared to those of [[MDA]] and other entactogens.
@@ Line 159: / Line 159: @@
 ==Reagent results==
-Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The following test results are from [https://www.protestkit.eu/results/ protestkit].
+Exposing compounds to the reagents gives a colour change which is indicative of the compound under test.
 {| class="wikitable"
 !Compound
@@ Line 175: / Line 175: @@
 |6-APB
 |Purple
-|Purple to black
+|Purple - black
-|Purple to black
+|Purple - black
 |Black
 |Purple
@@ Line 187: / Line 187: @@
 |6-APB succinate
 |Purple
-|Purple to black
+|Purple - black
-|Purple to black
+|Purple - black
 |Black
 |Purple