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Ketobemidone: Difference between revisions
>IJUSTPOPPEDAXAN Fixed base effects for real this time |
>IJUSTPOPPEDAXAN Added disconnective effects |
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The synthesis occurs by alkylating (3-methoxyphenyl)acetonitrile with bis(2-chloroethyl)methylamine, followed by a reaction with ethylmagnesium bromide, and finally O-demethylation with hydrobromic acid. | The synthesis occurs by alkylating (3-methoxyphenyl)acetonitrile with bis(2-chloroethyl)methylamine, followed by a reaction with ethylmagnesium bromide, and finally O-demethylation with hydrobromic acid. | ||
==Pharmacology== | ==Pharmacology== | ||
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==Subjective effects== | ==Subjective effects== | ||
{{effectStub}} | {{effectStub}} | ||
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{{effects/base | {{effects/base | ||
|{{effects/physical| | |{{effects/physical| | ||
*'''[[Effect::Sedation]]''' | *'''[[Effect::Sedation]]''' | ||
*'''[[Effect::Dizziness]]''' | *'''[[Effect::Dizziness]]''' | ||
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|{{effects/cognitive| | |{{effects/cognitive| | ||
*'''[[Effect::Cognitive euphoria]]''' | *'''[[Effect::Cognitive euphoria]]''' | ||
*'''[[Effect::Anxiety suppression]]''' | *'''[[Effect::Anxiety suppression]]''' | ||
*'''[[Effect::Confusion]]''' | *'''[[Effect::Confusion]]''' | ||
*'''[[Effect::Irritability]]''' - While opioids are well known for their ability to improve mood, they can also have the paradoxical effect of increasing the user's sensitivity to irritable stimuli. This can manifest as aloofness and sudden outbursts of anger and aggression (colloquially known as "opiate rage"). It appears to occur more frequently during the comedown of the experience and/or with heavy use. | *'''[[Effect::Irritability]]''' - While opioids are well known for their ability to improve mood, they can also have the paradoxical effect of increasing the user's sensitivity to irritable stimuli. This can manifest as aloofness and sudden outbursts of anger and aggression (colloquially known as "opiate rage"). It appears to occur more frequently during the comedown of the experience and/or with heavy use. | ||
}} | |||
{{effects/disconnective| | |||
*'''[[Effect::Cognitive disconnection]]''' | |||
*'''[[Effect::Physical disconnection]]''' | |||
}} | }} | ||
{{effects/visual| | {{effects/visual| | ||
====Suppressions==== | ====Suppressions==== | ||
*'''[[Effect::Double vision]]''' - At high doses, the eyes unfocus and re-focus uncontrollably. This creates a blurred effect and double vision that is present no matter where one focuses their eyes. This can be so intense it becomes impossible to read or drive. | *'''[[Effect::Double vision]]''' - At high doses, the eyes unfocus and re-focus uncontrollably. This creates a blurred effect and double vision that is present no matter where one focuses their eyes. This can be so intense it becomes impossible to read or drive. | ||
*'''[[Effect::Acuity suppression]]''' | *'''[[Effect::Acuity suppression]]''' | ||
====Hallucinatory States==== | ====Hallucinatory States==== | ||
*'''[[Effect::Internal hallucination]]''' - One may experience a state of semi-consciousness and [[hypnagogia]] during heavy dosage nodding which results in dream-like states and up to level 3 [[Lucid_dreaming#Internally_sourced_sensory_input|imagery]]. This is often accompanied by ill-defined [[geometry]]. | *'''[[Effect::Internal hallucination]]''' - One may experience a state of semi-consciousness and [[hypnagogia]] during heavy dosage nodding which results in dream-like states and up to level 3 [[Lucid_dreaming#Internally_sourced_sensory_input|imagery]]. This is often accompanied by ill-defined [[geometry]]. | ||
}} | |||
}} | }} | ||