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Ketobemidone: Difference between revisions
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'''Ketobemidone''' (also known by the brand names '''Ketogan''', and '''Ketorax''') is a synthetic [[Opioids|opioid]] substance of the [[Substituted piperidines|piperidine]] class. It is used to treat severe pain (like cancer pain, postoperative pain, gallstone pain, and kidney pain). | '''Ketobemidone''' (also known by the brand names '''Ketogan''', and '''Ketorax''') is a synthetic [[Opioids|opioid]] substance of the [[Substituted piperidines|piperidine]] class. It is used to treat severe pain (like cancer pain, postoperative pain, gallstone pain, and kidney pain). Its effectiveness against pain is in the same range as morphine, and it also has some NMDA-antagonist properties imparted, in part, by its metabolite norketobemidone.<ref>Ebert B, Thorkildsen C, Andersen S, Christrup LL, Hjeds H (September 1998). "Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists". ''Biochemical Pharmacology''. '''56''' (5): 553–9. doi:10.1016/S0006-2952(98)00088-4. <nowiki>PMID 9783723</nowiki>.</ref> | ||
It is marketed in Denmark, Iceland, Norway and Sweden and is used for severe pain.<ref>Brayfield A, ed. (9 January 2017). "Ketobemidone Hydrochloride: Martindale: The Complete Drug Reference". ''MedicinesComplete''. London, UK: Pharmaceutical Press.</ref> | |||
==History and culture== | ==History and culture== | ||