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Ketobemidone: Difference between revisions
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'''Ketobemidone''' (also known by the brand names '''Ketogan''', and '''Ketorax''') is a synthetic [[Opioids|opioid]] substance of the [[Substituted piperidines|piperidine]] class. It is used to treat severe pain (like cancer pain, postoperative pain, gallstone pain, and kidney pain). | '''Ketobemidone''' (also known by the brand names '''Ketogan''', and '''Ketorax''') is a synthetic [[Opioids|opioid]] substance of the [[Substituted piperidines|piperidine]] class. It is used to treat severe pain (like cancer pain, postoperative pain, gallstone pain, and kidney pain). | ||
==History and culture== | ==History and culture== | ||
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==Pharmacology== | ==Pharmacology== | ||
Ketobemidone is metabolized in the liver by N-dedemethylation, ringhydroxylation, O-methylation, and O-conjugation. The principal phase 1 reaction is N-demethylation. Primary metabolites of ketobemidone are norketobemidone, 4'-hydroxyketobemidone, and hydroxymethoxyketobemidone. The metabolites' pharmacological activity is unknown.<ref>https://bok.fass.se/LIF/product?userType=0&nplId=19930507000075</ref> | |||
==Subjective effects== | ==Subjective effects== | ||
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*[[Dissociative]] | *[[Dissociative]] | ||
==References== | |||
== References == | |||
<references /> | <references /> | ||