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3-HO-PCE: Difference between revisions
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===Experience reports=== | ===Experience reports=== | ||
There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here: | There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here: | ||
* [https://www.erowid.org/experiences/subs/exp_3HOPCE.shtml Erowid Experience Vaults: 3-HO-PCE] | |||
*[https://www.erowid.org/experiences/subs/exp_3HOPCE.shtml Erowid Experience Vaults: 3-HO-PCE] | |||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
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It is strongly recommended that one exercise extreme caution and [[responsible drug use|harm reduction]] practices when using this substance. | It is strongly recommended that one exercise extreme caution and [[responsible drug use|harm reduction]] practices when using this substance. | ||
*Users should avoid taking the drug multiple days in a row or becoming dependent/addicted to it as this seems to be the main common factor in the observed incidences of severe adverse effects. | *Users should avoid taking the drug multiple days in a row or becoming dependent/addicted to it as this seems to be the main common factor in the observed incidences of severe adverse effects. | ||
*The recommended dosage range should not be exceeded as high doses can trigger these effects as well. | *The recommended dosage range should not be exceeded as high doses can trigger these effects as well. | ||
*Users should start with extremely low doses and work their way up as slowly as possible. [[Volumetric liquid dosing|Volumetric liquid dosing]] should preferably be used due to the substance's potency; most standard milligram scales cannot accurately weigh out doses below 10-15mg.<ref>3-HO-PCE (Tripsit) | https://wiki.tripsit.me/wiki/3-HO-PCE</ref> | *Users should start with extremely low doses and work their way up as slowly as possible. [[Volumetric liquid dosing|Volumetric liquid dosing]] should preferably be used due to the substance's potency; most standard milligram scales cannot accurately weigh out doses below 10-15mg.<ref>3-HO-PCE (Tripsit) | https://wiki.tripsit.me/wiki/3-HO-PCE</ref> | ||
*[[Compulsive redosing]] before one has fully sobered up is not recommended and can result in too high of a dose, which can potentially produce serious adverse physical side effects. | *[[Compulsive redosing]] before one has fully sobered up is not recommended and can result in too high of a dose, which can potentially produce serious adverse physical side effects. | ||
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In terms of its long-term health effects when used repeatedly and excessively for extended periods of time, 3-HO-PCE is likely to exhibit similar bladder and urinary tract problems to those produced by [[ketamine]], albeit to a lesser extent. This has been speculated to be due to the fact 3-HO-PCE is far more potent than ketamine so significantly less of material needs to be consumed. Symptoms of dissociative-induced cystitis can become extremely serious and can be described as: | In terms of its long-term health effects when used repeatedly and excessively for extended periods of time, 3-HO-PCE is likely to exhibit similar bladder and urinary tract problems to those produced by [[ketamine]], albeit to a lesser extent. This has been speculated to be due to the fact 3-HO-PCE is far more potent than ketamine so significantly less of material needs to be consumed. Symptoms of dissociative-induced cystitis can become extremely serious and can be described as: | ||
*'''Urinary frequency''' - Urinary frequency is the need to empty the bladder every few minutes. | *'''Urinary frequency''' - Urinary frequency is the need to empty the bladder every few minutes. | ||
*'''Urinary urgency''' - This can be described as a sudden, compelling need to urinate. | *'''Urinary urgency''' - This can be described as a sudden, compelling need to urinate. | ||
*'''Urinary pressure''' - This is experienced as a constant sensation of fullness in the bladder that is unrelieved by urination. | *'''Urinary pressure''' - This is experienced as a constant sensation of fullness in the bladder that is unrelieved by urination. | ||
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==Legal status== | ==Legal status== | ||
{{legalStub}} | {{legalStub}} | ||
*'''Germany:''' 3-HO-PCE is not a controlled substance under the BtMG.<ref>http://www.gesetze-im-internet.de/btmg_1981/anlage_i.html</ref> It is legal, as long as it is not sold for human consumption, according to §2 AMG.<ref>https://www.gesetze-im-internet.de/amg_1976/__2.html</ref> | *'''Germany:''' 3-HO-PCE is not a controlled substance under the BtMG.<ref>http://www.gesetze-im-internet.de/btmg_1981/anlage_i.html</ref> It is legal, as long as it is not sold for human consumption, according to §2 AMG.<ref>https://www.gesetze-im-internet.de/amg_1976/__2.html</ref> | ||
*'''Sweden''': 3-HO-PCE is not a controlled substance for research purposes. It is illegal to consume. | |||
*'''Switzerland:''' 3-HO-PCE is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | *'''Switzerland:''' 3-HO-PCE is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | ||
*'''Turkey:''' 3-HO-PCE is a classed as drug and is illegal to possess, produce, supply, or import.<ref>Cumhurbaşkanı Kararı CK Karar Sayısı : 1335 | https://resmigazete.gov.tr/eskiler/2019/07/20190720-19.pdf</ref> | *'''Turkey:''' 3-HO-PCE is a classed as drug and is illegal to possess, produce, supply, or import.<ref>Cumhurbaşkanı Kararı CK Karar Sayısı : 1335 | https://resmigazete.gov.tr/eskiler/2019/07/20190720-19.pdf</ref> | ||
*'''United Kingdom:''' 3-HO-PCE is a class B drug in the UK and is illegal to possess, produce, supply, or import. As a derivative of 1-Phenylcyclohexylamine where the amine has been replaced with a 1-piperidyl group, further substituted in the phenyl ring with a hydroxy substituent, it is covered by the arylcyclohexylamine generic clause added to the Misuse of Drugs Act by S.I. 2013/239, which came into effect on the 26th February 2013.<ref>The Misuse of Drugs Act 1971 (Amendment) Order 2013 (Legislation.gov.uk) | http://www.legislation.gov.uk/uksi/2013/239/introduction/made</ref> | *'''United Kingdom:''' 3-HO-PCE is a class B drug in the UK and is illegal to possess, produce, supply, or import. As a derivative of 1-Phenylcyclohexylamine where the amine has been replaced with a 1-piperidyl group, further substituted in the phenyl ring with a hydroxy substituent, it is covered by the arylcyclohexylamine generic clause added to the Misuse of Drugs Act by S.I. 2013/239, which came into effect on the 26th February 2013.<ref>The Misuse of Drugs Act 1971 (Amendment) Order 2013 (Legislation.gov.uk) | http://www.legislation.gov.uk/uksi/2013/239/introduction/made</ref> | ||
==See also== | ==See also== | ||
*[[Responsible use]] | *[[Responsible use]] | ||
**[[Volumetric dosing]] | **[[Volumetric dosing]] | ||
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==External links== | ==External links== | ||
*[https://isomerdesign.com/PiHKAL/explore.php?id=968 3-HO-PCE (Isomer Design)] | *[https://isomerdesign.com/PiHKAL/explore.php?id=968 3-HO-PCE (Isomer Design)] | ||
===Discussion=== | ===Discussion=== | ||
*[http://bluelight.org/vb/threads/812314-The-Big-amp-Dandy-3-HO-PCE-Thread The Big & Dandy 3-HO-PCE Thread (Bluelight)] | *[http://bluelight.org/vb/threads/812314-The-Big-amp-Dandy-3-HO-PCE-Thread The Big & Dandy 3-HO-PCE Thread (Bluelight)] | ||
*[https://web.archive.org/web/20170111011440*/https://www.vice.com/en_us/article/interview-with-ketamine-chemist-704-v18n2 Interview with a Ketamine Chemist (VICE)] | *[https://web.archive.org/web/20170111011440*/https://www.vice.com/en_us/article/interview-with-ketamine-chemist-704-v18n2 Interview with a Ketamine Chemist (VICE)] | ||
==Literature== | ==Literature== | ||
* Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis, 6(7–8), 614–632. https://doi.org/10.1002/dta.1620 | |||
*Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis, 6(7–8), 614–632. https://doi.org/10.1002/dta.1620 | |||
==References== | ==References== | ||