This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Promethazine: Difference between revisions
>IJUSTPOPPEDAXAN |
>IJUSTPOPPEDAXAN Added dry mouth physical effect |
||
| Line 19: | Line 19: | ||
Promethazine is a direct antagonist of histamine H1 receptors, whereas [[diphenhydramine]] is an inverse agonist. It is also an antagonist of muscarinic acetylcholine receptors, which is likely the cause of sedation and delirium that occurs with higher doses. It blocks dopaminergic D2 receptors, but weakly. {{citation needed}} | Promethazine is a direct antagonist of histamine H1 receptors, whereas [[diphenhydramine]] is an inverse agonist. It is also an antagonist of muscarinic acetylcholine receptors, which is likely the cause of sedation and delirium that occurs with higher doses. It blocks dopaminergic D2 receptors, but weakly. {{citation needed}} | ||
==Subjective effects== | ==Subjective effects== | ||
{{Preamble/SubjectiveEffects}} | {{Preamble/SubjectiveEffects}} | ||
| Line 35: | Line 33: | ||
*'''[[Effect::Nausea suppression]]''' | *'''[[Effect::Nausea suppression]]''' | ||
*'''[[Effect::Dry mouth]]''' | |||
}} | }} | ||