Ayahuasca: Difference between revisions
>David Hedlund ===Potential antidepressant effects=== PMID: 29903051, https://clinicaltrials.gov/ct2/show/NCT02914769 |
>Tracer Grammatics. MAOI is not a chemical class |
||
Line 1: | Line 1: | ||
{{SubstanceBox/Ayahuasca}} | {{SubstanceBox/Ayahuasca}} | ||
{{SummarySheet}} | {{SummarySheet}} | ||
'''Ayahuasca''' (pronounced /eye-uh-WAHS-kuh/ and also known as '''Yagé''') is an umbrella term that refers to a wide variety of traditional and modern brews and infusions of natural plant sources that produce powerful psychoactive or [[hallucinogenic]] effects. Of these, it most commonly consists of a [[DMT]]-containing plant source in combination with one that contains an [[ | '''Ayahuasca''' (pronounced /eye-uh-WAHS-kuh/ and also known as '''Yagé''') is an umbrella term that refers to a wide variety of traditional and modern brews and infusions of natural plant sources that produce powerful psychoactive or [[hallucinogenic]] effects. Of these, it most commonly consists of a [[DMT]]-containing plant source in combination with one that contains an [[MAOI]] or [[RIMA]] (typically sources like [[Harmala_alkaloids#Banisteriopsis_caapi|B. caapi vine]] or [[Harmala_alkaloids#Peganum_harmala_.28Syrian_Rue.29|syrian rue]]) to produce uniquely potent, sometimes medicinal, [[psychoactive class::psychedelic]] effects. | ||
The co-consumption of an MAOI agent is necessary for the combination to work, as the DMT molecule (which is a [[monoamine]] closely related to [[serotonin]]) is rendered almost entirely inactive when digested by itself due to the presence of [[monoamine]] oxidase enzymes in the stomach, which rapidly degrades it.<ref>http://www.sciencedirect.com/science/article/pii/S0040402006012373</ref> | The co-consumption of an MAOI agent is necessary for the combination to work, as the DMT molecule (which is a [[monoamine]] closely related to [[serotonin]]) is rendered almost entirely inactive when digested by itself due to the presence of [[monoamine]] oxidase enzymes in the stomach, which rapidly degrades it.<ref>http://www.sciencedirect.com/science/article/pii/S0040402006012373</ref> |